Sveinung Berntsen Stølevik

• Tarabar, Zaklina; Børøsund, Elin; Fosstveit, Sindre Herskedal; Berntsen, Sveinung; Hagen, Milada & Vistad, Ingvild (2026). Factors Associated With the Use of the Lifestyle and Empowerment Techniques in Survivorship of Gynecologic Oncology (LETSGO) mHealth App in Routine Follow-Up After Gynecologic Cancer Treatment: Observational Study. JMIR Cancer. 12, s. 1–14. doi: 10.2196/89918. Fulltekst i vitenarkiv Vis sammendrag

  Background Mobile health (mHealth) apps offer new opportunities to support cancer survivors in managing their health, adopting healthier lifestyles, and increasing awareness of recurrence symptoms. However, despite their potential, little is known about survivors’ use of such tools in routine follow-up care, or which factors are associated with their engagement. Objective The aim of the present study was to identify survivor characteristics associated with the use of the Lifestyle and Empowerment Techniques in Survivorship of Gynecologic Oncology (LETSGO) app. In addition, we aimed to describe engagement patterns among gynecologic cancer survivors during the first year of follow-up after treatment. Methods App data from 378 participants in the intervention group of the LETSGO multicenter clinical trial were included in the analysis. Using multiple logistic regression, we analyzed app data from the first year of LETSGO app use to identify participant characteristics associated with use. In addition, we described the frequency of user interactions with app features and identified the most frequently used features during the first year of the intervention in a subset of 49 participants with complete app log data. Results Of the 378 participants in the intervention group, 267 (70.6%) used the LETSGO app at least twice and were defined as app users. The median age of app users was 63 (53-70) years vs 70 (60-78) years among app nonusers ( P <.001). App use was associated with younger age (odds ratio [OR] 0.96 per year, 95% CI 0.93‐0.99; P =.003), higher education (OR 2.2, 95% CI 1.1‐4.6; P =.03), and having ovarian cancer (OR 2.9; 95% CI 1.1‐7.5; P =.03). The LETSGO app included a monthly reminder for symptom self-registration, and monthly peaks in the symptom monitoring feature corresponded with the timing of this reminder. App log data from the full first year of the intervention were available for 49 participants. Among these, user engagement was highest for the physical activity and activity goal-setting features, whereas the disease information feature showed steady but less frequent use. Conclusions Our findings indicate that LETSGO app use was associated with survivor characteristics such as age, education level, and cancer type. Considering user characteristics when tailoring mHealth apps may support user engagement in digital follow-up care and inform the development of mHealth tools that better align with survivors’ needs and preferences. Engagement with the LETSGO app during the first year of follow-up among a subset of participants with complete app log data was highest for the physical activity and activity goal-setting features. The pattern of symptom registration following reminders indicates that scheduled prompts may support regular app engagement, while steady use of the disease information feature suggests an ongoing need for accessible health information during follow-up.

• Munns, Alexandra; Feron, Jack; Duda, Joan; Fosstveit, Sindre Herskedal; Joyce, Kelsey E. & Rahman, Foyzul [Vis alle 12 forfattere av denne artikkelen] (2026). Similar exercise adherence and physical fitness outcomes are observed across distinct motivation profiles in older adults participating in a home-based structured exercise programme. European Review of Aging and Physical Activity. ISSN 1813-7253. 23. doi: 10.1186/s11556-026-00421-1. Fulltekst i vitenarkiv Vis sammendrag

  Background Motivation and self-efficacy are well-established predictors of engagement and persistence within structured exercise programmes. Yet it remains unclear whether these psychological factors predict objective adherence metrics and associated fitness outcomes within home-based exercise programmes for older adults. Methods This study adopted a person-centred approach to examine whether distinct psychological profiles predict objective adherence and fitness outcomes following a 26-week home-based exercise programme in 88 older adults (age = 67.2 ± 5.5 years). Objective adherence was defined as compliance with the prescribed exercise volume and quantified using cumulative metabolic equivalent minutes (MET-mins) derived from heart rate data reflecting session intensity and duration across the programme, as opposed to behavioural self-report measures. Psychological profiles were generated using latent profile analysis based on autonomous motivation, controlled motivation, and exercise self-efficacy. Results Two profiles were identified: an autonomous and highly confident profile characterised by high selfefficacy and autonomous motivation, and a moderately autonomous and confident profile characterised by lower self-efficacy and autonomous motivation. Controlled motivation was similar between groups. Profiles did not differ in demographic or physiological characteristics at baseline. Adherence was high and comparable across the two profiles for all indices (e.g., cumulative MET-mins: 129 ± 66% vs. 116 ± 38%). Furthermore, both profiles demonstrated significant and comparable improvements in cardiorespiratory fitness (V̇O₂peak), handgrip strength, flexibility (chair sit-and-reach; back scratch), and mobility (8-foot up-and-go). Conclusions Baseline differences in self-efficacy and autonomous motivation among older adults did not significantly predict adherence or fitness outcomes within a structured, well-supported home-based exercise programme. The programme incorporated consistent objective monitoring of exercise behaviour, along with regular guidance and feedback from the research team delivered through scheduled participant contact. This level of structured behavioural support may have reduced the influence of psychological profile membership on exercise adherence and fitness outcomes, resulting in comparable positive outcomes across participants. Future research should investigate whether motivation profiles become more predictive of long-term adherence and sustained fitness outcomes once external behavioural support is reduced or withdrawn.

• Fosstveit, Sindre Herskedal; Feron, Jack; Seiler, Hilde Lohne; Joyce, Kelsey E.; Segaert, Katrien & Lucas, Samuel J.E. [Vis alle 7 forfattere av denne artikkelen] (2026). Impact of adherence to six-month home-based HIIT on cardiorespiratory fitness in older adults. BMC sports science, medicine and rehabilitation. 18(1). doi: 10.1186/s13102-026-01750-5. Fulltekst i vitenarkiv Vis sammendrag

  Background High-intensity interval training (HIIT) was originally designed to improve athletic performance, but a growing body of research over the past decade has highlighted its positive impact on various other health outcomes. However, concerns exist regarding HIIT’s suitability for those unaccustomed to regular exercise, as its high intensity may impact tolerance and adherence. Therefore, this study aimed to assess the associations between various objective adherence metrics and the resultant changes in peak oxygen uptake (V̇O2PEAK) and lactate threshold (LT) in older adults completing six-month home-based HIIT. Methods Healthy older adults (n = 233, 60–84 years, 54% female) were randomized to six-month, thrice-weekly home-based HIIT or a passive control group. Adherence in the HIIT group was objectively monitored using a Polar watch and heart rate sensor and quantified as frequency (sessions/week), intensity (minutes ≥ 80% HRPEAK/session), duration (session duration, min), and total adherence (cumulative MET-min; overall exercise volume summed across sessions from session duration and mean %HRPEAK). For each metric, adherence was expressed as a percentage of completion relative to the planned amount. V̇O2PEAK and LT were assessed using a modified Balke treadmill protocol to volitional exhaustion. To account for multicollinearity, partial least squares regression (PLSR) models assessed associations between adherence metrics and changes in V̇O2PEAK or LT. Results The PLSR analysis, accounting for baseline V̇O2PEAK, age, sex, and country where data-collection took place, revealed a positive association between post-test V̇O2PEAK and total adherence (Selectivity fractions (SF) = 0.70 [0.19; 0.93]), frequency adherence (SF = 0.54 [0.08; 0.86]), and intensity adherence (SF = 0.44 [0.07; 0.80]), but not with duration adherence (SF = 0.11 [− 0.08; 0.54]). For LT, PLSR analysis revealed no associations with any adherence metrics. Conclusions Superior HIIT adherence (i.e., total, frequency, and intensity) was associated with larger V̇O2PEAK gains in older adults. Notably, total adherence demonstrated the strongest predictive contribution among the adherence metrics, suggesting that overall exercise volume may be especially relevant for improving V̇O2PEAK in this context. In contrast, adherence metrics did not predict changes in LT, despite the exercise group experiencing significant LT improvements, indicating that LT adaptations were not strongly explained by variation in HIIT adherence in this sample.

• Fosstveit, Sindre Herskedal; Vistad, Ingvild; Skorstad, Mette & Berntsen, Sveinung (2026). Long-Term Engagement With a Physical Activity App Among Gynecologic Cancer Survivors in the LETSGO Trial: 12-Month Prospective, Multicenter, Quasi-Experimental Study. JMIR mhealth and uhealth. 14. doi: 10.2196/84838. Fulltekst i vitenarkiv Vis sammendrag

  Background: Physical activity (PA) alleviates many treatment-related side effects in gynecologic cancer survivors, yet long-term PA levels remain low. Mobile health interventions can support self-management and increase PA levels; however, evidence from real-world, year-long engagement with smartphone apps in this population is still limited. Objective: The aim of this study is to describe 12-month user engagement with the PA component of a smartphone app implemented within a partially nurse-led routine follow-up in a real-world cohort of gynecologic cancer survivors. Methods: This descriptive study analyzed server-generated log data from the intervention arm of the prospective, multicenter, quasi-experimental LETSGO (Lifestyle and Empowerment Techniques in Survivorship of Gynecologic Oncology) trial (NCT04122235). Between December 2019 and July 2022, 378 cancer survivors (ovarian, endometrial, cervical, vulvar, or vaginal cancer) from 5 Norwegian hospitals were enrolled in the intervention arm and were offered the app plus a Garmin Vivofit 4 activity tracker alongside standard consultations. Primary outcomes for this study were (1) weekly PA registrations (objective step counts from the activity tracker and self-reported PAs) and (2) temporal patterns of step logging during each cancer survivor’s first 52 weeks postenrollment. Secondary analyses compared baseline characteristics of app users (≥2 wk of PA logging) and nonusers. Results: Of 378 eligible participants (mean age 63, SD 13 y; BMI 28.5, SD 6.4 kg/m²), 272 (72%) logged at least 2 weeks of PA, and 225 (60%) synchronized objective step data. Mean daily steps were 5657 (SD 2799; median 5533, IQR 3499‐7498). Step tracking dominated app use (mean 21, SD 16 logged wk), followed by self-reported walking (mean 23, SD 19 wk) and resistance training (mean 15, SD 16 wk). Weekly step-logger counts fell around study weeks 16, 32, and 44, but rebounded by 30 to 50 participants within 3 weeks, indicating episodic rather than permanent disengagement. App users were younger (mean difference –6.7 y, 95% CI –9.6 to –3.9; P<.001), more often employed (χ²1=12.7; P<.001), and more likely to have higher education (χ²2=13.6; P<.001) than nonusers. Tumor type and treatment modality were not associated with engagement. Conclusions: In a routine-care setting, nearly three-quarters of gynecologic cancer survivors engaged repeatedly with an app-supported PA module over 12 months, although mean PA levels were modest and participation was more prevalent among younger, employed, and more highly educated participants. Engagement followed an ebb-and-flow pattern, suggesting that built-in re-engagement prompts and equity-focused onboarding are needed to sustain and broaden participation. These findings support the feasibility of blended mobile health follow-up while highlighting the importance of adaptive strategies to promote long-term PA adherence and bridge the digital divide among cancer survivors.

• Strandberg, Emelie; Vikmoen, Olav; Svindland, Karianne Vassbakk; Scheie, Atle Wendel; Ødemark, Hege Nymo & Henriksson, Anna [Vis alle 8 forfattere av denne artikkelen] (2026). The Effect of Strength Training During Chemotherapy in Women With Breast Cancer on Serum Cytokine Concentrations and Skeletal Muscle Autophagy-Related Proteins. European Journal of Sport Science (EJSS). ISSN 1746-1391. 26(7). doi: 10.1002/ejsc.70213. Fulltekst i vitenarkiv Vis sammendrag

  To evaluate whether strength training during chemotherapy alters (1) serum cytokines and (2) skeletal muscle autophagy- and heat-shock-related proteins in women with breast cancer. Exploratory analyses assessed associations between changes in physiological outcomes (muscle strength, cardiorespiratory fitness, and capillary density) and biomarker responses, and among cytokine changes. Women with breast cancer were randomized to strength training (n = 23) or usual care (n = 17). The training group completed supervised strength training twice weekly during chemotherapy; usual care maintained habitual physical activity. Assessments were performed pre-chemotherapy (T0) and post-chemotherapy/intervention (T1). Serum cytokines (IFN-γ, IL-1RA, IL-6, IL-8, IL-10, IL-17, MCP-1, TNF-α) were quantified, and muscle biopsies were analyzed for autophagy- and heat-shock-related proteins. In the strength training group, mean ± SD IL-6 increased from 1.21 ± 0.47 to 1.69 ± 0.71 pg/mL and IL-17 from 1.24 ± 0.25 to 2.18 ± 0.87 pg/mL. IFN-γ also increased in the training group (14.4 ± 8.6 to 28.8 ± 17.3 pg/mL), however, the group×time interaction was not statistically significant. In the usual care group, IL-6 and IL-17 decreased. No changes were observed in other cytokines or in autophagy- or heat-shock-related proteins. Exploratory analyses showed no associations between changes in strength and autophagy proteins, cardiorespiratory fitness and cytokines, or capillary density and cytokines. Strength training during chemotherapy did not alter selected skeletal muscle autophagy- or heat-shock-related proteins, despite group differences in IL-6 and IL-17 over time. The clinical and mechanistic significance of these cytokine shifts remains uncertain and should be evaluated in larger studies with additional time points and complementary immune and muscle outcomes.

• Sundfør, Hanne Beate; Stenling, Andreas; Bere, Elling Tufte; Fyhri, Aslak; Stavnsbo, Mette & Berntsen, Sveinung (2026). Exploring the relationship between e-cycling and additional moderate to vigorous intensity physical activity – A series of N-of-1 studies using accelerometer data. Journal of Cycling and Micromobility Research (JCMR). 9, s. 1–14. doi: 10.1016/j.jcmr.2026.100122. Fulltekst i vitenarkiv Vis sammendrag

  Cycling and e-cycling are promoted as sustainable transport solutions with potential public health benefits. Whether cycling adds to total physical activity (PA) or replaces other activity remains a key question. This relationship is commonly framed by three hypotheses: Compensation (cycling replaces existing PA), Independence (cycling adds to PA), and Generalization (cycling increases PA in other domains). Although previous research generally suggests that active transport does not displace other PA, evidence remains limited due to cross-sectional designs and inadequate objective measures of cycling. This study examined whether (e-)cycling contributes to additional moderate-to-vigorous physical activity (MVPA) in daily life. Employees enrolled in an e-bike leasing programme at the University of Agder, Norway (n = 18) wore a thigh-mounted accelerometer (Fibion SENS®) for 52–85 consecutive days. Using an exploratory N-of-1 design, individual time-series analyses (i.e., dynamic regression modelling) assessed within-individual associations between cycling and MVPA within and across days. For most participants, e-cycling for work-related commuting was not associated with reductions in other MVPA, indicating no evidence of compensation. Only one participant showed partial compensation. Similar patterns were found for total cycling (electric and conventional): most showed no associations, while three displayed negative and two positive associations with additional MVPA. These findings align with the Independence hypothesis, suggesting that (e-)cycling adds to overall physical activity rather than displacing it, while also highlighting individual variation. By applying devise-based monitoring and within-person analyses in real-life settings, this study adds to the evidence base for cycling and e-cycling as health-promoting and sustainable mobility strategies.

• Henriksson, Anna; Stenling, Andreas; Mazzoni, Anne Sophie; Sjövall, Katarina; Börjeson, Sussanne & Berntsen, Sveinung [Vis alle 10 forfattere av denne artikkelen] (2026). What is the adherence to an exercise intervention during (neo-)adjuvant chemotherapy among Swedish patients with breast cancer? Data from the Phys-Can randomised controlled trial. BMJ Open. 16(5). doi: 10.1136/bmjopen-2025-105540. Fulltekst i vitenarkiv Vis sammendrag

  Objectives While exercise adherence is known to vary during cancer treatment, little is known about what predicts these changes during chemotherapy or within individual treatment cycles for breast cancer. We examined changes in adherence and its predictors (1) across chemotherapy treatment and (2) within treatment cycles in women undergoing (neo-)adjuvant chemotherapy for breast cancer. Design This study is based on data from the Phys-Can multicentre parallel randomised trial. Setting The exercise intervention was conducted at public gyms in three Swedish university cities. Participants 178 women undergoing (neo-)adjuvant chemotherapy without any chemotherapy treatment delays and had any adherence data were included in the analysis. Interventions Participants in the Phys-Can trial were randomised to either high or low-to-moderate intensity combined endurance and resistance training. Primary outcome The primary outcome variable for this secondary analysis of Phys-Can trial data was adherence to endurance and resistance training. Bayesian multilevel growth curve models were used to examine adherence to resistance and endurance training throughout the chemotherapy treatment period and within chemotherapy cycles. Potential predictors of adherence included exercise intensity, chemotherapy dose, muscle strength, body mass index, cardiorespiratory fitness, fatigue and age. Results are reported with 95% credibility intervals (CrIs). Results Adherence to endurance and resistance training declined on average across the chemotherapy treatment by 1% (95% CrI −1.5, −0.5) and 5.2% (95% CrI −6.8, −3.6), respectively, per week. Adherence decreased within the chemotherapy treatment cycle by 2.4% for endurance (95% CrI −4.2, −0.7) and 6.1% (95% CrI −8.2, −4.1) for resistance training, respectively. Higher baseline fitness predicted better adherence to endurance exercise (β=1.2, 95% CrI 0.1, 2.3), while high-intensity training predicted a steeper decline (β=−1.2, 95% CrI −2.2, 0.2). No significant predictors were found for adherence to resistance training over time. Conclusions Women with breast cancer may require additional support to maintain exercise adherence during the later stages of chemotherapy and during the second and third weeks of their chemotherapy cycles. Those with lower pretreatment fitness levels may benefit from more intensive support to sustain engagement in exercise.

• Dahlqvist, Heléne; Ekdahl, Ann; Wiklund, Emma; Jong, Mats; Berntsen, Sveinung & Fernee, Carina Ribe [Vis alle 7 forfattere av denne artikkelen] (2026). Managing Late and Long-Term Effects Among Swedish Adolescents and Young Adults Affected by Cancer Following a Wilderness Intervention: Reconnecting with Self and Meaning Through Nature’s Unconditional Presence – A Qualitative Study. Cancer Control. ISSN 1073-2748. 33, s. 1–18. doi: 10.1177/10732748251414202. Fulltekst i vitenarkiv Vis sammendrag

  Introduction Adolescents and Young Adults (AYAs) affected by cancer are at risk of experiencing late and long-term effects following cancer diagnosis and treatment. While structured interventions have demonstrated potential benefits for well-being during the intervention itself, little is known about how AYAs affected by cancer engage with and experience nature in their everyday lives beyond the formal program context. The aim of this study was to explore how a selected group of AYAs affected by cancer—who had participated in a nature-based intervention (the WAYA program)—experience nature and its role in supporting and managing late and long-term effects of cancer and its treatment, beyond the context of the program itself. Method This qualitative study explored the experiences of nature following the WAYA intervention among AYAs affected by cancer. Data were collected by focus group interviews at a three-month follow-up, using participant-selected photographs as visual prompts to elicit reflection on how nature supports management of late and long-term effects of cancer. A photovoice-inspired approach guided discussion questions and facilitated individual and collective meaning-making. Interviews were audio-recorded, transcribed verbatim, and analyzed using qualitative content analysis. Results The analysis of this study showed one theme: Reconnecting with self and meaning through nature’s unconditional presence—beyond human connection. The theme comprises the two categories Nature as a resource for inner balance and Nature as a meaningful companion , and five sub-categories : Managing by being mindful, Managing by experiencing rest and being calm, Experiencing metaphoric recognition, Sparking comfort, hope and positive emotions, and Nature as a space without obligations. Conclusion This study explored how AYAs affected by cancer engage with nature beyond formal programs, revealing its potential in better management of late and long-term effects. These findings can inform low-threshold, personal meaningful, and sustainable approaches to clinical practice, well-being, and rehabilitation for this vulnerable group.

• Ax, Anna-Karin; Stenling, Andreas; Berntsen, Sveinung; Börjeson, Sussanne; Nordin, Karin & Demmelmaier, Ingrid [Vis alle 7 forfattere av denne artikkelen] (2025). Longitudinal Profiles and Predictors of Physical Activity in Cancer Survivors Post-Exercise Intervention: A 5-Year Follow-Up of the Phys-Can RCT. Integrative Cancer Therapies. ISSN 1534-7354. 24. doi: 10.1177/15347354251362447. Fulltekst i vitenarkiv Vis sammendrag

  Regular physical activity improves health outcomes in cancer survivors; however, maintaining recommended levels of moderate-to-vigorous intensity physical activity (MVPA) post-treatment is challenging, even for those participating in exercise intervention studies. Understanding long-term MVPA patterns and predictors can guide strategies to promote sustained physical activity in this population. We aimed to describe objectively measured MVPA-profiles over 5 years in cancer survivors who participated in a 6-month exercise intervention during cancer treatment, and to identify baseline predictors of profile belonging. Methods: Data were derived from the multicenter randomized controlled trial Phys-Can, including participants with breast, colorectal or prostate cancer. Objective measures of MVPA were conducted at baseline, post-intervention, and at 1-, 2-, and 5-year follow-ups. Longitudinal latent profile analysis was used to identify MVPA profiles, and multinomial logistic regression to examine potential baseline predictors of profile belonging. Results: Among 556 participants, 4 longitudinal MVPA profiles were identified: Low and stable (18.0%), Medium and stable (40.8%), High and decreasing (28.4%), and Very high and stable (12.8%). Compared to the Very high and stable MVPA profile, participants in the Low and stable MVPA profile were more likely to be women (OR = 20.64) or have higher BMI (OR = 1.41) or lower cardiorespiratory fitness (OR = 0.69) at baseline. Conclusion: Cancer survivors who are women or have a higher BMI and/or low cardiorespiratory fitness prior to cancer treatment are at greater risk of maintaining low MVPA levels over time. These groups may require targeted support to enhance and sustain physical activity during survivorship.

• Vikmoen, Olav; Strandberg, Emelie; Svindland, Karianne Vassbakk; Henriksson, Anna; Mazzoni, Anne Sophie & Berntsen, Sveinung [Vis alle 7 forfattere av denne artikkelen] (2025). Effects of Heavy-Load Strength Training During (Neo-)Adjuvant Chemotherapy on Cardiorespiratory Fitness, Aerobic Enzymes, Capillaries, Fatigue and Quality of Life in Women With Breast Cancer. The FASEB Journal. ISSN 0892-6638. 39(23). doi: 10.1096/fj.202502355R. Fulltekst i vitenarkiv Vis sammendrag

  To investigate the effects of heavy-load strength training during (neo-)adjuvant chemotherapy on cardiorespiratory fitness and muscle content of aerobic enzymes and capillaries, as well as to explore its effects on cancer-related fatigue and health-related quality of life (HR-QoL) in women with breast cancer. Women diagnosed with stage I–III breast cancer were randomized to a strength training group (ST, n = 23), performing supervised heavy-load training twice weekly during chemotherapy, or a usual care control group (CON, n = 17). Peak oxygen consumption (VO2peak), hemoglobin concentration ([Hb]), cancer-related fatigue, and HR-QoL were assessed and muscle biopsies of the vastus lateralis were collected before chemotherapy (T0) and after chemotherapy and training (T1). VO2peak and [Hb] decreased in both groups (VO2peak: ST: −5.7 [−11.4 to −0.1]%, p = 0.014; CON: −11.0 [−16.4 to −1.3]%, p = 0.0005), [Hb]: (ST: −6.3 [−11.2 to −1.3]%, p = 0.011; CON: −7.1 [−11.9 to −2.3]%, p = 0.007). Aerobic enzyme levels (COX4, CS, HADH combined) remained stable in ST but decreased in CON (−11.4 [−19.5 to −3.2]%, p = 0.003). The effect size (ES) (0.79) was moderate in favor of the strength training group. Capillaries were unchanged in ST but reduced in CON for type 2 fibers (capillaries around each fiber: −16 [−31 to −2]%, p = 0.04; capillaries around each fiber divided by fiber area: −19 [−34 to −5]%, p = 0.0138) with moderate ESs in favor of ST. Physical fatigue increased in CON but remained stable in ST. Strength training during chemotherapy mitigated reductions in capillary density and aerobic enzyme levels, as well as the rise in physical fatigue observed with usual care.

• Henriksen, Hege Berg; Kolle, Åshild; Stenling, Andreas; Paur, Ingvild; Bøhn, Siv Kjølsrud & Brøto, Pernille [Vis alle 9 forfattere av denne artikkelen] (2025). Spillover effect of a dietary intervention on physical activity in a randomized controlled trial with colorectal cancer patients. International Journal of Behavioral Nutrition and Physical Activity. 22, s. 1–13. doi: 10.1186/s12966-025-01757-0. Fulltekst i vitenarkiv Vis sammendrag

  Background Randomized controlled studies (RCTs) targeting dietary changes may also lead to other, untargeted changes in lifestyle habits, as spillover effects. In particular, the isolated impact of the dietary intervention may be difficult to separate due to spillover effects from changes in physical activity and physical function. Therefore, the aim of this study was to investigate the spillover effect of a one-year dietary intervention in post-surgery colorectal cancer patients by comparing the changes in physical activity and physical function between the diet intervention Group and the control group in a randomized controlled trial, called the CRC-NORDIET study. Methods Men and women, aged 50–80 years were randomized into either the intervention group (n=240) or the control group (n=229). Both groups received similar incentives on physical activity. Activity sensors were used to collect data on physical activity at baseline, 6 months, and 12 months. Physical function was estimated by results from handgrip strength, 30 s sit-to-stand test and 6-min walking test. Anthropometric measurements and body composition were also measured. Results We found a significantly higher increase in moderate-to-vigorous intensity physical activity (MVPA) of 0.18 h per day from baseline to 6 months in the diet intervention group compared to the control group, respectively. However, the spillover effect of the dietary intervention on physical activity diminished to 0.10 h per day at 12 months follow-up which was not statistically significantly different (p=0.24) from the control group. All measures of physical function increased in both groups from baseline to 6 months with no further increase at the 12-month follow-up. Conclusions The dietary intervention did not induce a significant spillover effect on physical activity after 12 months of baseline, which was the main timepoint of the intervention. Providing identical physical activity guidance to both study groups during the 12-month intensive dietary intervention period, ensured comparable levels of physical activity across both study groups. This approach facilitated the isolation and analysis of the dietary intervention’s effects on primary endpoints, as well as effects of behaviour interventions in secondary preventions, such as the CRCNORDIET study. Trial registration The study is registered on the National Institutes of Health Clinical Trials website (www.ClinicalTrials.gov; Identifier: NCT01570010)

• Meland, Eivind; Abildsnes, Eirik; Samdal, Gro Beate; Stea, Tonje Holte; Haugen, Tommy & Berntsen, Sveinung [Vis alle 7 forfattere av denne artikkelen] (2025). Changes in physical activity among overweight and obese Norwegian children aged 6–12: A non-randomized cluster-controlled trial. Scandinavian Journal of Public Health. ISSN 1403-4948. 53(8), s. 872–880. doi: 10.1177/14034948251315350. Fulltekst i vitenarkiv Vis sammendrag

  Aims: To explore whether a family-based intervention with playful activities among overweight and obese Norwegian children promoted moderate to vigorous and light physical activity compared with a waiting list control group, and to examine whether gross motor competence, isometric body mass index and motivational factors, as reported by the children and their parents, could explain changes observed during a six-month observation. Methods: A non-randomized cluster-controlled trial with 131 participants, 76 in the intervention group. Participants were aged 6–12 years, and 55 were boys. We performed linear regressions to compare the intervention and the control groups and adjusted linear models to examine predictors for outcomes with the groups merged into one cohort. Results: We could not demonstrate any intervention effect from the family-based activities. Moderate to vigorous physical activity levels were satisfactory at the start and were maintained during the observation period. None of the predictors could explain outcome status at six months, nor residual change of moderate to vigorous physical activity during the observation. We revealed that parental educational attainment, parental autonomous motivation and the participants’ experience of social support impacted light physical activity negatively after six months. Parental education also impacted the residual change of light physical activity negatively during the observation. Conclusions: The present family-based intervention to improve physical activity among overweight and obese children was ineffective. Baseline activity levels were already satisfactory. Paradoxically, factors such as parental socioeconomic status, autonomous motivation and self-reported support from parents and peers may be associated with diminished physical activity in such contexts. These unexpected findings need to be validated in further studies.

• Malnes, Lena; Haugen, Tommy; Nordbø, Emma Charlott Andersson; Ivarsson, Andreas; Kolle, Elin & Resaland, Geir Kåre [Vis alle 9 forfattere av denne artikkelen] (2025). Objectively measured environmental factors in relation to school travel mode among adolescents: a decision tree analysis. International Journal of Behavioral Nutrition and Physical Activity. 22. doi: 10.1186/s12966-025-01727-6. Fulltekst i vitenarkiv Vis sammendrag

  Background Understanding the factors that influence school travel mode choice is essential for promoting active travel among adolescents. Currently, there is a lack of research that effectively investigates the interactions between demographic and environmental factors on travel behavior. We aimed to investigate the associations between various demographic and environmental characteristics and the choice of school travel modes—walking, cycling, or motorized transport—among adolescents, across the winter and summer seasons. Methods Data from 1409 Norwegian adolescents, aged 14–15 years, who participated in the School In Motion project were analyzed. Self-reported travel modes and demographic characteristics were collected via questionnaires, while environmental characteristics were determined using Geographic Information Systems (GIS). A decision tree analysis was conducted utilizing the chi-squared automatic interaction detection algorithm to discern patterns in the data. The present study has a cross-sectional design. Results During summer, the predominant travel modes were cycling (39%), walking (37%), and motorized transport (24%). Gender was associated with travel mode choices over short distances (< 1.6 km), with girls favoring walking and boys favoring cycling. For longer commutes, steep inclines were associated with reduced walking and cycling, while higher traffic exposure was associated with increased cycling. During winter, walking (50%) was the most common mode, followed by motorized travel (36%) and cycling (14%). Living near peers was associated with increased walking and cycling among girls. For commutes exceeding 2 km, factors such as available bus transit, more streetlights, the absence of steep hills, and higher urban centrality were linked to increased walking and cycling. Conclusions The findings indicated a complex pattern of demographic and environmental factors influencing active travel, with environmental factors becoming increasingly important as commuting distances increased. These findings highlight the importance of considering the interactions of various factors to effectively promote active travel, especially for adolescents undertaking longer commutes. Trial registration Clinicaltrials.gov ID no: NCT03817047. Registered on: January 25, 2019 (retrospectively registered).

• Vistad, Ingvild; Skorstad, Mette; Berntsen, Sveinung; Demmelmaier, Ingrid; Bjørge, Line & Poll-Franse, Lonneke V. Van De [Vis alle 17 forfattere av denne artikkelen] (2025). Empowerment and quality of life in gynecological cancer survivors: Outcomes from a multicenter quasi-experimental cohort study from Norway (the LETSGO trial). Cancer. ISSN 0008-543X. 131(16). doi: 10.1002/cncr.70040. Fulltekst i vitenarkiv Vis sammendrag

  Background: Increasing outpatient demands and unmet patient needs necessitate personalized follow-up care for cancer survivors. This study investigated whether a self-management–focused follow-up model improves empowerment and quality of life (QoL) in gynecological cancer survivors compared to standard follow-up. Methods: Twelve Norwegian hospitals participated in this cohort study. Patients initiating routine follow-up after primary treatment were eligible and allocated to either intervention or standard care follow-up groups based on their treatment hospital. The intervention included nurse-led consultations using coaching techniques for education on symptom monitoring and healthy lifestyle, alternated with physician-led consultations and access to a mobile app. Standard follow-up consisted of physician-led consultations only. The primary outcome was change in patient empowerment over 12 months, measured with the self-monitoring and insight domain of the Health Education Impact Questionnaire (heiQ). Secondary outcomes included changes in remaining heiQ domains and QoL. Data were analyzed according to intention-to-treat principles using linear mixed effects models. Results: Among 741 participants (intervention: 378, standard: 363), baseline characteristics were comparable. At 12 months, no significant differences were observed in self-monitoring and insight (Δ = 0.02 [95% confidence interval (CI), –0.04 to 0.08]; effect sizes [ES] = 0.29). However, health-directed activity (Δ = 0.15 [95% CI, 0.04–0.25]; ES = 0.15), emotional well-being (Δ = 0.12 [95% CI, 0.02–0.20]; ES = 0.15), social functioning (Δ = 5.2 [95% CI, 1.1–9.3]; ES = 0.41), and physical functioning (Δ = 2.5 [95% CI, 0.0–5.0]; ES = 0.20) were significantly more improved in the intervention group. Conclusion: Lifestyle and Empowerment Techniques in Survivorship of Gynaecologic Oncology follow-up did not significantly impact self-monitoring and insight, but positively influenced other survivorship domains, indicating its potential for enhancing self-management and QoL in gynecological cancer survivors.

• Sundfør, Hanne Beate; Berntsen, Sveinung; Bere, Elling Tufte & Fyhri, Aslak (2024). The effects of subsidising e-bikes on mode share and physical activity - A natural experiment. Journal of Transport and Health. ISSN 2214-1405. 35(March 2024), s. 1–13. doi: 10.1016/j.jth.2023.101752. Fulltekst i vitenarkiv Vis sammendrag

  Introduction The promotion of increased cycling is a political goal in numerous countries due to its environmental and public health benefits. Initiatives to stimulate e-bike use, like subsidies, may be a relevant strategy. However, understanding of the effects of these subsidies remains limited. In the present study our aim was to investigate the short-term effects of subsidising e-bike purchases on mode share distribution, physical activity derived from daily travel, and overall levels of physical activity. Methods We used the 2020-subvention program in Oslo, Norway, as a natural experiment, employing a pre-post randomised group design. The trial group (N = 194) and control group (N = 2174) participated in a survey at two time points (in April and September 2021), which included a one-day travel diary and questions about physical activity over the previous week. Results Our findings revealed a significant 12.6 [7.2, 18.0] percentage point increase in bicycle mode share, followed by a decrease in the share of car and public transport usage of 10.1 [-15.9, −2.5] and 7.1 [-11.8, −2.4] percentage points. In terms of physical activity generated from daily travel, we observed a greater increase in e-cycling compared to the decrease in conventional cycling and walking, resulting in an overall rise in active transport. However, despite these findings, we did not detect a significant increase in overall physical activity resulting from this increased active mobility. Conclusion Initiatives such as subsidies for e-bikes may align with both environmental and public health goals, as the subvention led to an increase in the bicycle mode share and an overall rise in active transport. However, to assess the impact on overall physical activity, additional research utilising more precise measurements is needed.

• Fernandes, Eunice Gomes; Fosstveit, Sindre Herskedal; Feron, Jack; Rahman, Foyzul; Lucas, Samuel J.E. & Lohne-Seiler, Hilde [Vis alle 10 forfattere av denne artikkelen] (2024). Effects of increasing fitness through exercise training on language comprehension in monolingual and bilingual older adults: a randomized controlled trial. Aging, Neuropsychology and Cognition. ISSN 1382-5585. 32(4), s. 485–517. doi: 10.1080/13825585.2024.2435914. Fulltekst i vitenarkiv Vis sammendrag

  Exercise training has been proposed to counteract age-related cognitive decline through improvements in cardiorespiratory fitness (CRF hypothesis). Research has focused on cognitive domains like attention and processing speed, and one cross-sectional study reported a positive relationship between CRF and language production in older adults. In a randomized controlled trial, we investigated whether these benefits could extend to language comprehension in healthy older adults, and whether bilinguals, for whom language processing is more costly, would exhibit greater benefits than monolinguals. Eighty older English monolinguals and 80 older Norwegian-English bilinguals were randomized into either a 6-month exercise training group or into a passive control group. We assessed CRF (VO2peak) and language comprehension (reaction times to spoken word monitoring) in first (L1, all participants) and second language (L2, bilinguals only), before and after the intervention. We found that monolinguals in the exercise group (compared to the control group) were faster in comprehension following the intervention. Moreover, this effect was mediated by exercise-induced increases in VO2peak, supporting the CRF hypothesis. This extends previous cross-sectional research and establishes a causal link between exercise training and speeded comprehension in older monolinguals. However, despite inducing increased VO2peak, exercise training did not affect bilingual (L1 or L2) comprehension, and bilinguals in both groups were slower after the intervention period. Exploratory analyses suggested that this slowing may be driven by participants with low L2 proficiency, but further research is needed to examine whether bilingual language processing is in fact unaffected by exercise training and its consequent improvements in CRF.

• Feron, Jack; Rahman, Foyzul; Fosstveit, Sindre Herskedal; Joyce, Kelsey E; Gilani, Ahmed & Lohne-Seiler, Hilde [Vis alle 10 forfattere av denne artikkelen] (2024). Cerebral blood flow and arterial transit time responses to exercise training in older adults. NeuroImage. ISSN 1053-8119. 303. doi: 10.1016/j.neuroimage.2024.120919. Fulltekst i vitenarkiv
• Vikmoen, Olav; Strandberg, Emelie; Svindland, Karianne Vassbakk; Henriksson, Anna; Mazzoni, Anne-Sophie & Johansson, Birgitta [Vis alle 16 forfattere av denne artikkelen] (2024). Effects of heavy-load strength training during (neo-)adjuvant chemotherapy on muscle strength, muscle fiber size, myonuclei, and satellite cells in women with breast cancer. The FASEB Journal. ISSN 0892-6638. 38(13), s. 1–17. doi: 10.1096/fj.202400634R. Fulltekst i vitenarkiv
• Feron, Jack; Segaert, Katrien; Rahman, Foyzul; Fosstveit, Sindre Herskedal; Joyce, Kelsey E. & Gilani, Ahmed [Vis alle 10 forfattere av denne artikkelen] (2024). Determinants of cerebral blood flow and arterial transit time in healthy older adults. Aging. 16(18), s. 12473–12497. doi: 10.18632/aging.206112. Fulltekst i vitenarkiv
• Fosstveit, Sindre Herskedal; Berntsen, Sveinung; Feron, Jack; Joyce, Kelsey E.; Ivarsson, Andreas & Segaert, Katrien [Vis alle 8 forfattere av denne artikkelen] (2024). HIIT at Home: Enhancing Cardiorespiratory Fitness in Older Adults—A Randomized Controlled Trial. Scandinavian Journal of Medicine & Science in Sports. ISSN 0905-7188. 34(7), s. 1–14. doi: 10.1111/sms.14694. Fulltekst i vitenarkiv Vis sammendrag

  Background This study aimed to investigate the effectiveness of a 6-month home-based high-intensity interval training (HIIT) intervention to improve peak oxygen consumption (V̇O2peak) and lactate threshold (LT) in older adults. Methods Two hundred thirty-three healthy older adults (60–84 years; 54% females) were randomly assigned to either 6-month, thrice-weekly home-based HIIT (once-weekly circuit training and twice-weekly interval training) or a passive control group. Exercise sessions were monitored using a Polar watch and a logbook for objective and subjective data, respectively, and guided by a personal coach. The outcomes were assessed using a modified Balke protocol combining V̇O2peak and LT measures. General linear regression models assessed between-group differences in change and within-group changes for each outcome. Results There was a significant between-group difference in the pre-to-post change in V̇O2peak (difference: 1.8 [1.2; 2.3] mL/kg/min; exercise: +1.4 [1.0; 1.7] mL/kg/min [~5%]; control: −0.4 [−0.8; −0.0] mL/kg/min [approximately −1.5%]; effect size [ES]: 0.35). Compared with controls, the exercise group had lower blood lactate concentration (−0.7 [−0.9; −0.4] mmol/L, ES: 0.61), % of peak heart rate (−4.4 [−5.7; −3.0], ES: 0.64), and % of V̇O2peak (−4.5 [−6.1; −2.9], ES: 0.60) at the intensity corresponding to preintervention LT and achieved a higher treadmill stage (% incline) at LT (0.6 [0.3; 0.8]; ES: 0.47), following the intervention. Conclusion This study highlights the effectiveness of a home-based HIIT intervention as an accessible and equipment-minimal strategy to induce clinically meaningful improvements in cardiorespiratory fitness in older adults. Over 6 months, the exercise group showed larger improvements in all outcomes compared with the control group. Notably, the LT outcome exhibited a more pronounced magnitude of change than V̇O2peak.

• Fosstveit, Sindre Herskedal; Lohne-Seiler, Hilde; Feron, Jack; Lucas, Samuel J. E.; Ivarsson, Andreas & Berntsen, Sveinung (2024). The intensity paradox: A systematic review and meta-analysis of its impact on the cardiorespiratory fitness of older adults. Scandinavian Journal of Medicine & Science in Sports. ISSN 0905-7188. 34(2). doi: 10.1111/sms.14573. Fulltekst i vitenarkiv Vis sammendrag

  Aim The present systematic review and meta-analysis aimed to compare the effect of moderate- versus high-intensity aerobic exercise on cardiorespiratory fitness (CRF) in older adults, taking into account the volume of exercise completed. Methods The databases MEDLINE (Ovid), EMBASE (Ovid), and CENTRAL (Cochrane Library) were searched to identify randomized controlled trials (RCTs). Two reviewers extracted data and assessed bias. Comprehensive Meta-Analysis software calculated overall effect size, intensity differences, and performed meta-regression analyses using pre-to-post intervention or change scores of peak oxygen uptake (V̇O2peak). The review included 23 RCTs with 1332 older adults (intervention group: n = 932; control group: n = 400), divided into moderate-intensity (435 older adults) and high-intensity (476 older adults) groups. Results Meta-regression analysis showed a moderate, but not significant, relationship between exercise intensity and improvements in V̇O2peak after accounting for the completed exercise volume (β = 0.31, 95% CI = [−0.04; 0.67]). Additionally, studies comparing moderate- versus high-intensity revealed a small, but not significant, effect in favor of high-intensity (Hedges' g = 0.20, 95% CI = [−0.02; 0.41]). Finally, no significant differences in V̇O2peak improvements were found across exercise groups employing various methods, modalities, and intensity monitoring strategies. Conclusion Findings challenge the notion that high-intensity exercise is inherently superior and indicate that regular aerobic exercise, irrespective of the specific approach and intensity, provides the primary benefits to CRF in older adults. Future RCTs should prioritize valid and reliable methodologies for monitoring and reporting exercise volume and adherence among older adults.

• Jong, Miek C.; Fernee, Carina Ribe; Stenling, Andreas; Lown, E Anne; Berntsen, Sveinung & Victorson, David E. [Vis alle 7 forfattere av denne artikkelen] (2024). Protocol of a randomised controlled multicentre trial investigating the effectiveness and safety of a wilderness programme on the mental and physical well-being of adolescents and young adults affected by cancer: the WAYA-2 study. BMJ Open. 14(5). doi: 10.1136/bmjopen-2024-087626. Fulltekst i vitenarkiv Vis sammendrag

  Introduction Adolescents and young adults (AYAs) affected by cancer are an understudied group. Effective interventions are needed to support coping with the late effects of cancer, its treatment and to promote quality of life. Nature-based interventions may be promising in support of the self-management and health of AYAs affected by cancer. However, randomised controlled studies (RCTs) on the effectiveness of such interventions are lacking. We performed a first pilot RCT (n=42) that showed that it is feasible and safe to conduct such a study. Here, we propose a full-scale RCT to investigate the effectiveness and safety of a wilderness programme on the mental and physical health of AYAs affected by cancer.<p> <p>Methods and analysis Participants are 150 AYAs affected by cancer, aged 16–39 years, who will be randomised to a wilderness (n=75) or a hotel stay (n=75). The wilderness programme is an 8-day intervention including a 6-day wilderness expedition. This is followed 3months later by a 4-day intervention including a 2-day basecamp. Activities include hiking, backpacking, kayaking, rock climbing, mindfulness and bush-crafting. The comparison group is an 8-day hotel stay followed by a 4-day hotel stay (interventions include two travel days) at the same hotel after 3months. Primary outcomes are psychological well-being and nature connectedness up to 1 year after the study start. Secondary outcomes are quality of life, physical activity and safety parameters. <p>Ethics and dissemination The Swedish Ethical Review Authority approved the study protocol on 27 September 2023 (reference: 2023-05247-01). The recruitment started on 19 February 2024 and the first part is planned to end on 31 December 2027. Study results will be disseminated by means of scientific publications, presentations at conferences, popular articles, interviews, chronicles and books. News items will be spread via social media, websites and newsletters.

• Western, Benedikte; Ivarsson, Andreas; Vistad, Ingvild; Demmelmaier, Ingrid; Aaronson, Neil K. & Radcliffe, Gillian [Vis alle 47 forfattere av denne artikkelen] (2024). Dropout from exercise trials among cancer survivors—An individual patient data meta-analysis from the POLARIS study. Scandinavian Journal of Medicine & Science in Sports. ISSN 0905-7188. 34(2). doi: 10.1111/sms.14575. Fulltekst i vitenarkiv Vis sammendrag

  Introduction: The number of randomized controlled trials (RCTs) investigating the effects of exercise among cancer survivors has increased in recent years; however, participants dropping out of the trials are rarely described. The objective of the present study was to assess which combinations of participant and exercise program characteristics were associated with dropout from the exercise arms of RCTs among cancer survivors. Methods: This study used data collected in the Predicting OptimaL cAncer RehabIlitation and Supportive care (POLARIS) study, an international database of RCTs investigating the effects of exercise among cancer survivors. Thirty-four exercise trials, with a total of 2467 patients without metastatic disease randomized to an exercise arm were included. Harmonized studies included a pre and a posttest, and participants were classified as dropouts when missing all assessments at the post-intervention test. Subgroups were identified with a conditional inference tree. Results: Overall, 9.6% of the participants dropped out. Five subgroups were identified in the conditional inference tree based on four significant associations with dropout. Most dropout was observed for participants with BMI >28.4 kg/m2, performing supervised resistance or unsupervised mixed exercise (19.8% dropout) or had low-medium education and performed aerobic or supervised mixed exercise (13.5%). The lowest dropout was found for participants with BMI >28.4 kg/m2 and high education performing aerobic or supervised mixed exercise (5.1%), and participants with BMI ≤28.4 kg/m2 exercising during (5.2%) or post (9.5%) treatment. Conclusions: There are several systematic differences between cancer survivors completing and dropping out from exercise trials, possibly affecting the external validity of exercise effects.

• Western, Benedikte; Demmelmaier, Ingrid; Vistad, Ingvild; Hansen, Bjørge Hermann; Stenling, Andreas & Henriksen, Hege [Vis alle 9 forfattere av denne artikkelen] (2023). How many days of continuous physical activity monitoring reliably represent time in different intensities in cancer survivors. PLOS ONE. 18(4). doi: 10.1371/journal.pone.0284881. Fulltekst i vitenarkiv Vis sammendrag

  Background Physical activity (PA) monitoring is applied in a growing number of studies within cancer research. However, no consensus exists on how many days PA should be monitored to obtain reliable estimates in the cancer population. The objective of the present study was to determine the minimum number of monitoring days required for reliable estimates of different PA intensities in cancer survivors when using a six-days protocol. Furthermore, reliability of monitoring days was assessed stratified on sex, age, cancer type, weight status, and educational level. Methods Data was obtained from two studies where PA was monitored for seven days using the SenseWear Armband Mini in a total of 984 cancer survivors diagnosed with breast, colorectal or prostate cancer. Participants with ≥22 hours monitor wear-time for six days were included in the reliability analysis (n = 736). The intra-class correlation coefficient (ICC) and the Spearman Brown prophecy formula were used to assess the reliability of different number of monitoring days. Results For time in light PA, two monitoring days resulted in reliable estimates (ICC >0.80). Participants with BMI ≥25, low-medium education, colorectal cancer, or age ≥60 years required one additional monitoring day. For moderate and moderate-to-vigorous PA, three monitoring days yielded reliable estimates. Participants with BMI ≥25 or breast cancer required one additional monitoring day. Vigorous PA showed the largest within subject variations and reliable estimates were not obtained for the sample as a whole. However, reliable estimates were obtained for breast cancer survivors (4 days), females, BMI ≥30, and age <60 years (6 days). Conclusion Shorter monitoring periods may provide reliable estimates of PA levels in cancer survivors when monitored continuously with a wearable device. This could potentially lower the participant burden and allow for less exclusion of participants not adhering to longer protocols.

• Stavnsbo, Mette; Stenling, Andreas; Berntsen, Sveinung; Chinapaw, Mai J. M.; Hansen, Bjørge Hermann & Manios, Yannis [Vis alle 12 forfattere av denne artikkelen] (2023). Does an obesogenic family environment moderate the association between sports participation and body composition in children? The ENERGY project. Pediatric Obesity. ISSN 2047-6302. 18(7). doi: 10.1111/ijpo.13031. Fulltekst i vitenarkiv Vis sammendrag

  BackgroundPrevious research on the association between sports participation and body composition has shown mixed findings. The family home is considered one of the most influential environments on childhood obesity. Thus, the association between sports participation and body composition in children may be influenced by an obesogenic home environment.ObjectivesTo investigate if an obesogenic family environment moderates the association between sports participation and body composition in children.MethodsA total of 3999 children (54% girls; 11.6 ± 0.7 years) and their parent(s) were included from the ENERGY project. A composite obesogenic family environment risk score was created from 10 questionnaire items. Height, weight (to calculate body mass index), and waist circumference were obtained by trained researchers and used as indicators of body composition.ResultsThe composite risk score significantly moderated the association between sports participation and both waist circumference and body mass index. In children from families with moderate and high obesogenic risk, organized sports participation was significantly associated with smaller waist circumference (moderate risk: −0.29, 95% CI −0.45 to −0.14; high risk: −0.46, 95% CI −0.66 to −0.25) and lower body mass index (moderate risk: −0.10, 95% CI −0.16 to −0.04; high risk: −0.14, 95% CI −0.22 to −0.06), but not in children with a low obesogenic family risk score.ConclusionsEnrolling children in sports activities from an early age can be important for healthy weight maintenance, especially among children from obesogenic family environments.

• Ax, Anna-Karin; Husberg, Magnus; Johansson, Birgitta; Demmelmaier, Ingrid; Berntsen, Sveinung & Sjövall, Katarina [Vis alle 9 forfattere av denne artikkelen] (2023). Cost-effectiveness of different exercise intensities during oncological treatment in the Phys-Can RCT. Acta Oncologica. ISSN 0284-186X. 62(4), s. 414–421. doi: 10.1080/0284186X.2023.2200149. Fulltekst i vitenarkiv Vis sammendrag

  Background: Cost-effectiveness is important in the prioritisation between interventions in health care. Exercise is cost-effective compared to usual care during oncological treatment; however, the significance of exercise intensity to the cost-effectiveness is unclear. In the present study, we aimed to evaluate the long-term cost-effectiveness of the randomised controlled trial Phys-Can, a six-month exercise programme of high (HI) or low-to-moderate intensity (LMI) during (neo)adjuvant oncological treatment. Methods: A cost-effectiveness analysis was performed, based on 189 participants with breast, colorectal, or prostate cancer (HI: n¼99 and LMI: n¼90) from the Phys-Can RCT in Sweden. Costs were estimated from a societal perspective, and included cost of the exercise intervention, health care utilisation and productivity loss. Health outcomes were assessed as quality-adjusted life-years (QALYs), using EQ-5D-5L at baseline, post intervention and 12months after the completion of the intervention. Results: At 12-month follow-up after the intervention, the total cost per participant did not differ significantly between HI (e27,314) and LMI exercise (e29,788). There was no significant difference in health outcome between the intensity groups. On average HI generated 1.190 QALYs and LMI 1.185 QALYs. The mean incremental cost-effectiveness ratio indicated that HI was cost effective compared with LMI, but the uncertainty was large. Conclusions: We conclude that HI and LMI exercise have similar costs and effects during oncological treatment. Hence, based on cost-effectiveness, we suggest that decision makers and clinicians can consider implementing both HI and LMI exercise programmes and recommend either intensity to the patients with cancer during oncological treatment to facilitate improvement of health.

• Mazzoni, Anne-Sophie; Strandberg, Emelie; Börjeson, Sussanne; Sjövall, Katarina; Berntsen, Sveinung & Demmelmaier, Ingrid [Vis alle 7 forfattere av denne artikkelen] (2023). Reallocating sedentary time to physical activity: effects on fatigue and quality of life in patients with breast cancer in the Phys-Can project. Supportive Care in Cancer. ISSN 0941-4355. 31(2). doi: 10.1007/s00520-023-07614-9. Fulltekst i vitenarkiv
• Mazzoni, Anne-Sophie; Bjørke, Ann Christin Helgesen; Stenling, Andreas; Börjeson, Sussanne; Sjövall, Katarina & Berntsen, Sveinung [Vis alle 8 forfattere av denne artikkelen] (2023). The Role of Long-Term Physical Activity in Relation to Cancer-Related Health Outcomes: A 12-Month Follow-up of the Phys-Can RCT. Integrative Cancer Therapies. ISSN 1534-7354. 22, s. 1–10. doi: 10.1177/15347354231178869. Fulltekst i vitenarkiv Vis sammendrag

  Purpose: While moderate-to-vigorous intensity physical activity (MVPA) is associated with various health improvements shortly after completion of exercise interventions, it remains unclear which health benefits can be expected when MVPA levels are maintained in the long term in cancer survivors. We aimed to assess the associations of (1) MVPA level at 12-month follow-up and (2) long-term MVPA patterns (from immediately post-intervention to 12-month follow-up) with different cancer-related health outcomes. Methods: In the Physical training and Cancer (Phys-Can) RCT, 577 participants diagnosed with breast (78%), prostate (19%), or colorectal (3%) cancer were randomized to 6 months of exercise during curative cancer treatment. Accelerometer-assessed physical activity and outcome data (ie, cancer-related fatigue, health-related quality of life [HRQoL], anxiety and depression, functioning in daily life, cardiorespiratory fitness, sedentary time and sleep) were collected immediately post-intervention and at 12-month follow-up. Based on the sample’s median of MVPA immediately post-intervention (65 minutes/day) and the changes between the 2 measurement points, 4 categories with different long-term MVPA patterns were created: High & Increasing, High & Decreasing, Low & Increasing, and Low & Decreasing. Multiple linear regression analyses were performed for the analyses. Results: A total of 353 participants were included in the analyses. At 12-month follow-up, a higher MVPA level was significantly associated with lower fatigue in 3 domains (general fatigue [β = −.33], physical fatigue [β = −.53] and reduced activity [β = −.37]), higher cardiorespiratory fitness (β = .34) and less sedentary time (β = −.35). For long-term MVPA patterns, compared to the participants in the “Low & Decreasing” category, those in the “High & Increasing” category reported significantly lower fatigue in 3 domains (general fatigue [β = −1.77], physical fatigue [β = −3.36] and reduced activity [β = −1.58]), higher HRQoL (β = 6.84) and had less sedentary time (β = −1.23). Conclusion: Our results suggest that long-term physical activity is essential for improving health outcomes post-intervention in cancer survivors. Cancer survivors, including those who reach recommended MVPA levels, should be encouraged to maintain or increase MVPA post-intervention for additional health benefits.

• Fosstveit, Sindre Herskedal; Lindberg, Kolbjørn Andreas; Bjørnsen, Thomas; Sibayan, Erlend E.; Fjeller, Joachim S. & Løvold, Sondre [Vis alle 10 forfattere av denne artikkelen] (2023). Associations between Power Training-Induced Changes in Body Composition and Physical Function in Older Men: A Pre-Test–Post-Test Experimental Study. International Journal of Environmental Research and Public Health (IJERPH). ISSN 1661-7827. 20(22). doi: 10.3390/ijerph20227070. Fulltekst i vitenarkiv Vis sammendrag

  It is well-established that cross-sectional measurements of poor body composition are associated with impaired physical function and that power training effectively enhances total lean mass and physical function in older adults. However, it is unclear if power training-induced changes in body composition are associated with improved physical function in older adults. Aim: The present study investigated associations between body composition and physical function cross-sectionally and with power training-induced changes in older men. Methods: Forty-nine older men (68 ± 5 yrs) completed a 10-week biweekly power training intervention. Body composition was measured using dual-energy X-ray absorptiometry. Physical function was assessed as a composite Z-score combining measures from Sit-to-stand power, Timed up-and-go time, and loaded and unloaded Stair-climbing time (15 steps). Linear and quadratic regression analyses were performed to assess associations between body composition and physical function. Results: At baseline, total (R2 = 0.11, p < 0.05) and percentage body fat (R2 = 0.15, p < 0.05) showed a non-linear relationship with physical function. The apex of the quadratic regression for body composition was 21.5% body fat. Furthermore, there was a non-linear relationship between changes in body fat percentage and physical function from pre- to post-intervention (R2 = 0.15, p < 0.05). Conclusion: The present study’s findings indicate that participants with a body composition of ~20% body fat displayed the highest level of physical function at baseline. Furthermore, despite small pre–post changes in body fat, the results indicate that those who either preserved their body fat percentage or experienced minor alterations observed the greatest improvements in physical function.

• Henriksson, Anna; Strandberg, Emelie; Stenling, Andreas; Mazzoni, Anne-Sophie; Sjövall, Katarina & Börjeson, Sussanne [Vis alle 10 forfattere av denne artikkelen] (2023). Does inflammation markers or treatment type moderate exercise intensity effects on changes in muscle strength in cancer survivors participating in a 6-month combined resistance- and endurance exercise program? Results from the Phys-Can trial. BMC sports science, medicine and rehabilitation. 15. doi: 10.1186/s13102-023-00617-3. Fulltekst i vitenarkiv Vis sammendrag

  Background: Resistance exercise has a beneficial impact on physical function for patients receiving oncological treatment. However, there is an inter-individual variation in the response to exercise and the tolerability to high-intensity exercise. Identifying potential moderating factors, such as inflammation and treatment type, for changes in muscle strength is important to improve the effectiveness of exercise programs. Therefore, we aimed to investigate if inflammation and type of oncological treatment moderate the effects of exercise intensity (high vs. low-moderate) on muscular strength changes in patients with breast (BRCA) or prostate cancer (PRCA). Methods: Participants with BRCA (n = 286) and PRCA (n = 65) from the Physical training and Cancer study (Phys-Can) were included in the present study. Participants performed a combined resistance- and endurance exercise program during six months, at either high or low-moderate intensity. Separate regression models were estimated for each cancer type, with and without interaction terms. Moderators included in the models were treatment type (i.e., neo/adjuvant chemotherapy—yes/no for BRCA, adjuvant androgen deprivation therapy (ADT)—yes/no for PRCA)), and inflammation (interleukin 6 (IL6) and tumor necrosis factor-alpha (TNFα)) at follow-up. Results: For BRCA, neither IL6 (b = 2.469, 95% CI [− 7.614, 12.552]) nor TNFα (b = 0.036, 95% CI [− 6.345, 6.418]) levels moderated the effect of exercise intensity on muscle strength change. The same was observed for chemotherapy treatment (b = 4.893, 95% CI [− 2.938, 12.724]). Similarly, for PRCA, the effect of exercise intensity on muscle strength change was not moderated by IL6 (b = − 1.423, 95% CI [− 17.894, 15.048]) and TNFα (b = − 1.905, 95% CI [− 8.542, 4.732]) levels, nor by ADT (b = − 0.180, 95% CI [− 11.201, 10.841]). Conclusions: The effect of exercise intensity on muscle strength is not moderated by TNFα, IL6, neo/adjuvant chemotherapy, or ADT, and therefore cannot explain any intra-variation of training response regarding exercise intensity (e.g., strength gain) for BRCA or PRCA in this setting.

• Malnes, Lena; Berntsen, Sveinung; Kolle, Elin; Ivarsson, Andreas; Dyrstad, Sindre Mikal & Resaland, Geir Kåre [Vis alle 8 forfattere av denne artikkelen] (2023). School-based physical activity in relation to active travel – a cluster randomized controlled trial among adolescents enrolled in the school in motion study in Norway. International Journal of Behavioral Nutrition and Physical Activity. 20(1). doi: 10.1186/s12966-023-01534-x. Fulltekst i vitenarkiv Vis sammendrag

  Background Active travel and school settings are considered ideal for promoting physical activity. However, previous research suggests limited effect of school-based interventions on overall physical activity levels among adolescents. The relationship between physical activity in different domains remains inconclusive. In this study, we examined the effects of adding two weekly hours of school-based physical activity on active travel rates. Method We analyzed data from 1370 pupils in the 9th-grade participating in the cluster RCT; the School In Motion (ScIM) project. Intervention schools (n = 19) implemented 120 min of class-scheduled physical activity and physical education, in addition to the normal 2 hours of weekly physical education in the control schools (n = 9), for 9 months. Active travel was defined as pupils who reported walking or cycling to school, while motorized travel was defined as pupils who commuted by bus or car, during the spring/summer half of the year (April–September), or autumn/winter (October–February). The participants were categorized based on their travel mode from pretest to posttest as; maintained active or motorized travel (“No change”), changing to active travel (motorized-active), or changing to motorized travel (active-motorized). Multilevel logistic regression was used to analyze the intervention effect on travel mode. Results During the intervention period, most participants maintained their travel habits. In total, 91% of pupils maintained their travel mode to school. Only 6% of pupils switched to motorized travel and 3% switched to active travel, with small variations according to season and trip direction. The intervention did not seem to influence the likelihood of changing travel mode. The odds ratios for changing travel habits in spring/summer season were from active to motorized travel 1.19 [95%CI: 0.53–2.15] and changing from motorized to active travel 1.18 [0.30–2.62], compared to the “No change” group. These findings were consistent to and from school, and for the autumn/winter season. Conclusion The extra school-based physical activity does not seem to affect rates of active travel among adolescents in the ScIM project.

• Lindberg, Kolbjørn Andreas; Lohne-Seiler, Hilde; Fosstveit, Sindre Herskedal; Sibayan, Erlend E.; Fjeller, Joachim S. & Løvold, Sondre [Vis alle 12 forfattere av denne artikkelen] (2022). Effectiveness of individualized training based on force–velocity profiling on physical function in older men. Scandinavian Journal of Medicine & Science in Sports. ISSN 0905-7188. 32(6), s. 1013–1025. doi: 10.1111/sms.14157. Fulltekst i vitenarkiv Vis sammendrag

  The study aimed to investigate the effectiveness of an individualized power training program based on force–velocity (FV) profiling on physical function, muscle morphology, and neuromuscular adaptations in older men. Forty-nine healthy men (68 ± 5 years) completed a 10-week training period to enhance muscular power. They were randomized to either a generic power training group (GPT) or an individualized power training group (IPT). Unlike generic training, individualized training was based on low- or high-resistance exercises, from an initial force–velocity profile. Lower-limb FV profile was measured in a pneumatic leg-press, and physical function was assessed as timed up-and-go time (TUG), sit-to-stand power, grip strength, and stair-climbing time (loaded [20kg] and unloaded). Vastus lateralis morphology was measured with ultrasonography. Rate of force development (RFD) and rate of myoelectric activity (RMA) were measured during an isometric knee extension. The GPT group improved loaded stair-climbing time (6.3 ± 3.8 vs. 2.3% ± 7.3%, p = 0.04) more than IPT. Both groups improved stair-climbing time, sit to stand, and leg press power, grip strength, muscle thickness, pennation angle, fascicle length, and RMA from baseline (p < 0.05). Only GPT increased loaded stair-climbing time and RFD (p < 0.05). An individualized power training program based on FV profiling did not improve physical function to a greater degree than generic power training. A generic power training approach combining both heavy and low loads might be advantageous through eliciting both force- and velocity-related neuromuscular adaptions with a concomitant increase in muscular power and physical function in older men.

• Vikmoen, Olav; Wiestad, Tor Helge; Thormodsen, Inger; Nordin, Karin; Berntsen, Sveinung & Demmelmaier, Ingrid [Vis alle 8 forfattere av denne artikkelen] (2022). Effects of High and Low-To-Moderate Intensity Exercise During (Neo-) Adjuvant Chemotherapy on Muscle Cells, Cardiorespiratory Fitness, and Muscle Function in Women With Breast Cancer: Protocol for a Randomized Controlled Trial. JMIR Research Protocols. 11(11). doi: 10.2196/40811. Fulltekst i vitenarkiv
• Bjørke, Ann Christin Helgesen; Buffart, Laurien M.; Raastad, Truls; Demmelmaier, Ingrid; Stenling, Andreas & Nordin, Karin [Vis alle 7 forfattere av denne artikkelen] (2022). Exploring Moderators of the Effect of High vs. Low-to-Moderate Intensity Exercise on Cardiorespiratory Fitness During Breast Cancer Treatment – Analyses of a Subsample From the Phys-Can RCT. Frontiers in Sports and Active Living. 4. doi: 10.3389/fspor.2022.902124. Fulltekst i vitenarkiv Vis sammendrag

  Introduction: The results from the physical training and cancer randomized controlled trial (Phys-Can RCT) indicate that high intensity (HI) strength and endurance training during (neo-)adjuvant cancer treatment is more beneficial for cardiorespiratory fitness (CRF, measured as peak oxygen uptake [VO2peak]) than low-to-moderate intensity (LMI) exercise. Adherence to the exercise intervention and demographic or clinical characteristics of patients with breast cancer undergoing adjuvant treatment may moderate the exercise intervention effect on VO2peak. In this study, the objective was to investigate whether baseline values of VO2peak, body mass index (BMI), time spent in moderate- to vigorous-intensity physical activity (MVPA), physical fatigue, age, chemotherapy treatment, and the adherence to the endurance training moderated the effect of HI vs. LMI exercise on VO2peak. Materials and Methods: We used data collected from a subsample from the Phys-Can RCT; women who were diagnosed with breast cancer and had a valid baseline and post-intervention VO2peak test were included (n = 255). The exercise interventions from the RCT included strength and endurance training at either LMI, which was continuous endurance training at 40–50% of heart rate reserve (HRR), or at HI, which was interval training at 80–90% of HRR, with similar exercise volume in the two groups. Linear regression analyses were used to investigate moderating effects using a significance level of p < 0.10. Statistically significant interactions were examined further using the Johnson–Neyman (J-N) technique and regions of significance (for continuous variables) or box plots with adjusted means of post-intervention VO2peak (for binary variables). Results: Age, as a continuous variable, and adherence, dichotomized into < or > 58% based on median, moderated the effect of HI vs. LMI on CRF (B = −0.08, 95% CI [−0.16, 0.01], pinteraction = 0.06, and B = 1.63, 95% CI [−0.12, 3.38], pinteraction = 0.07, respectively). The J-N technique and regions of significance indicated that the intervention effect (HI vs. LMI) was positive and statistically significant in participants aged 61 years or older. Baseline measurement of CRF, MVPA, BMI, physical fatigue, and chemotherapy treatment did not significantly moderate the intervention effect on CRF. Conclusion: Women with breast cancer who are older and who have higher adherence to the exercise regimen may have larger effects of HI exercise during (neo-)adjuvant cancer treatment on CRF.

• Ax, Anna-Karin; Husberg, Magnus; Johansson, Birgitta; Demmelmaier, Ingrid; Berntsen, Sveinung & Sjövall, Katarina [Vis alle 9 forfattere av denne artikkelen] (2022). Long-term resource utilisation and associated costs of exercise during (neo)adjuvant oncological treatment: the Phys-Can project. Acta Oncologica. ISSN 0284-186X. 61(7), s. 888–896. doi: 10.1080/0284186X.2022.2075238. Fulltekst i vitenarkiv Vis sammendrag

  Background: Exercise during oncological treatment is beneficial to patient health and can counteract the side effects of treatment. Knowledge of the societal costs associated with an exercise intervention, however, is limited. The aims of the present study were to evaluate the long-term resource utilisation and societal costs of an exercise intervention conducted during (neo)adjuvant oncological treatment in a randomised control trial (RCT) versus usual care (UC), and to compare high-intensity (HI) versus low-to-moderate intensity (LMI) exercise in the RCT. Methods: We used data from the Physical Training and Cancer (Phys-Can) project. In the RCT, 577 participants were randomised to HI or to LMI of combined endurance and resistance training for 6 months, during oncological treatment. The project also included 89 participants with UC in a longitudinal observational study. We measured at baseline and after 18 months. Resource utilisation and costs of the exercise intervention, health care, and productivity loss were compared using analyses of covariance (RCT vs. UC) and t test (HI vs. LMI). Results: Complete data were available for 619 participants (RCT HI: n ¼ 269, LMI: n ¼ 265, and UC: n ¼ 85). We found no difference in total societal costs between the exercise intervention groups in the RCT and UC. However, participants in the RCT had lower rates of disability pension days (p < .001), corresponding costs (p ¼ .001), and pharmacy costs (p ¼ .018) than the UC group. Nor did we find differences in resource utilisation or costs between HI and LMI exercise int the RCT. Conclusion: Our study showed no difference in total societal costs between the comprehensive exercise intervention and UC or between the exercise intensities. This suggests that exercise, with its welldocumented health benefits during oncological treatment, produces neither additional costs nor savings.

• Schauer, Tim; Henriksson, Anna; Strandberg, Emelie; Lindman, Henrik; Berntsen, Sveinung & Demmelmaier, Ingrid [Vis alle 9 forfattere av denne artikkelen] (2022). Pre-treatment levels of inflammatory markers and chemotherapy completion rates in patients with early-stage breast cancer. International Journal of Clinical Oncology. ISSN 1341-9625. 28. doi: 10.1007/s10147-022-02255-0. Fulltekst i vitenarkiv Vis sammendrag

  Background Chemotherapy efcacy is largely dependent on treatment adherence, defned by the relative dose intensity (RDI). Identifcation of new modifable risk factors associated with low RDI might improve chemotherapy delivery. Here, we evaluated the association between low RDI and pre-chemotherapy factors, including patient- and treatment-related characteristics and markers of infammation. Methods This exploratory analysis assessed data from 267 patients with early-stage breast cancer scheduled to undergo (neo-)adjuvant chemotherapy included in the Physical training and Cancer (Phys-Can) trial. The association between low RDI, defned as<85%, patient-related (age, body mass index, co-morbid condition, body surface area) and treatment-related factors (cancer stage, receptor status, chemotherapy duration, chemotherapy dose, granulocyte colony-stimulating factor) was investigated. Analyses further included the association between RDI and pre-chemotherapy levels of interleukin (IL)-6, IL-8, IL-10, C-reactive protein (CRP) and Tumor Necrosis Factor-alpha (TNF-α) in 172 patients with available blood samples. Results An RDI of<85% occurred in 31 patients (12%). Univariable analysis revealed a signifcant association with a chemotherapy duration above 20 weeks (p<0.001), chemotherapy dose (p=0.006), pre-chemotherapy IL-8 (OR 1.61; 95% CI (1.01; 2.58); p=0.040) and TNF-α (OR 2.2 (1.17; 4.53); p=0.019). In multivariable analyses, infammatory cytokines were signifcant association with low RDI for IL-8 (OR: 1.65 [0.99; 2.69]; p=0.044) and TNF-α (OR 2.95 [1.41; 7.19]; p=0.007). Conclusions This exploratory analysis highlights the association of pre-chemotherapy IL-8 and TNF-α with low RDI of chemotherapy for breast cancer. IL-8 and TNF-α may therefore potentially help to identify patients at risk for experiencing dose reductions.

• Malnes, Lena Hansen; Haugen, Tommy; Hansen, Bjørge Hermann; Kolle, Elin & Berntsen, Sveinung (2022). Establishing the Convergent Validity of the Travel Habit Questions in the Health Behavior in School-Aged Children Questionnaire by Quantifying Active Travel in Norwegian Adolescents. Frontiers in Sports and Active Living. 4. doi: 10.3389/fspor.2022.761723. Fulltekst i vitenarkiv Vis sammendrag

  Background: Active travel (cycling or walking to school) can be a substantial part of adolescents' daily physical activity. Research on transport activities primarily relies on self-reported indices of travel mode and travel time. However, many researchers do not report the psychometric properties of their instruments. The Health Behavior in School-aged Children (HBSC) questionnaire is a commonly used instrument, but the items in this questionnaire on travel habits have not yet been validated. The present study was conducted to investigate the convergent validity and agreement between the HBSC items and a travel diary on (1) transport mode to and from school and (2) travel time to school. Methods: The study sample consisted of 50 participants in the 9th grade (15 ± 0.3 years, 62% girls) from seven Norwegian schools. Outcome variables included transport mode and travel time derived from the HBSC items and a five-day travel diary. Convergent validity was assessed by evaluating Cohen's kappa for travel mode and the correlation coefficient (Spearman Rho) for travel time. Simple agreement calculations between the two measurement methods were also conducted. Results: The association between the HBSC questionnaire and the diary for travel mode to and from school was κ = 0.63 (P < 0.001) and κ = 0.77 (P < 0.001), respectively. The total agreement between the HBSC questionnaire and the diary for was 78%. However, the agreement was higher for walking (88%) and cycling (91%) than for motorized transport (67%). For travel time, the Spearman correlation coefficient was ρ = 0.60 (P < 0.001) between the HBSC questionnaire and the diary. The total agreement on travel time was 67%; however, active commuters (86%) seemed to more accurately estimated travel time than motorized commuters (55%). Conclusion: Although the overall agreement between the HBSC questionnaire and the diary for mode of transport was 78%, the HBSC questionnaire may underestimate the prevalence of motorized transport compared to walking and cycling.

• Skorstad, Mette; Vistad, Ingvild; Fegran, Liv; Berntsen, Sveinung & Johannessen, Berit (2022). Nurse-led consultations reinforced with eHealth technology: a qualitative study of the experiences of patients with gynecological cancer. BMC Nursing. 21. doi: 10.1186/s12912-022-01104-9. Fulltekst i vitenarkiv Vis sammendrag

  Background: During the last decade, the health care profession has moved toward personalized care and has focused on the diversity of survivorship needs after initial cancer treatment. Health care providers encourage empowering patients to participate actively in their own health management and survivorship. Consequently, we developed and piloted a new follow-up model for patients at a Norwegian hospital, referred to as the Lifestyle and Empowerment Techniques in Survivorship of Gynecologic Oncology (LETSGO) model. Using LETSGO, a dedicated nurse replaces the physician in every second follow-up consultation, providing patients who have undergone cancer treatment with self-management techniques that are reinforced with eHealth technology via a specially designed app. Encouraging behavioral change and evaluating the late effects of treatment and recurrence symptoms are central components of self-management techniques. In addition, the app encourages physical activity and positive lifestyle changes, helps identify recurrence-related symptoms, and provides reminders of activity goals. This study aims to investigate experiences with nurse-led consultations supported by eHealth technology among the patients who piloted the LETSGO intervention. Methods: Semi-structured qualitative interviews were conducted to analyze the participants’ experiences with the LETSGO intervention after six to seven months. Results: The participants in the LETSGO pilot felt safe and well cared for. They thought the nurse was less busy than the doctors appear to be, which made it easy for them to share any cancer-related challenges. Many participants reported increased empowerment and confidence in recognizing symptoms of cancer recurrence, and participants who used the app regularly were motivated to increase their physical activity levels. However, the participants also experienced some limitations and technical errors with the app. Conclusions: Generally, the participants positively received the nurse-led consultations and eHealth technology, but an intervention study is required for further evaluation. In addition, the reported technical app errors should be resolved and tested prior to eHealth application implementation. Regardless, this study may be useful in planning personalized survivorship care studies.

• Brooke, Hannah L.; Mazzoni, Anne-Sophie; Buffart, Laurien M.; Berntsen, Sveinung; Nordin, Karin & Demmelmaier, Ingrid (2022). Patterns and determinants of adherence to resistance and endurance training during cancer treatment in the Phys-Can RCT. BMC sports science, medicine and rehabilitation. 14. doi: 10.1186/s13102-022-00548-5. Fulltekst i vitenarkiv
• Solberg, Runar Barstad; Steene-Johannessen, Jostein; Fagerland, Morten; Anderssen, Sigmund Alfred; Berntsen, Sveinung & Resaland, Geir Kåre [Vis alle 9 forfattere av denne artikkelen] (2021). Aerobic fitness mediates the intervention effects of a school-based physical activity intervention on academic performance. The school in Motion study – A cluster randomized controlled trial. Preventive Medicine Reports. 24. doi: 10.1016/j.pmedr.2021.101648. Fulltekst i vitenarkiv Vis sammendrag

  Little information exists on the mechanism of how physical activity interventions effects academic performance. We examined whether the effects of a school-based physical activity intervention on academic performance were mediated by aerobic fitness. The School in Motion study was a nine-month cluster randomized controlled trial between September 2017 and June 2018. Students from 30 Norwegian lower secondary schools (N = 2,084, mean age [SD] = 14 [0.3] years) were randomly assigned into three groups: the Physically Active Learning (PAL) intervention (n = 10), the Don’t Worry—Be Happy (DWBH) intervention (n = 10), or control (n = 10). Aerobic fitness was assessed by the Andersen test and academic performance by national tests in reading and numeracy. Mediation was assessed according to the causal steps approach using linear mixed models. In the PAL intervention, aerobic fitness partially mediated the intervention effect on numeracy by 28% from a total effect of 1.73 points (95% CI: 1.13 to 2.33) to a natural direct effect of 1.24 points (95% CI: 0.58 to 1.91), and fully mediated the intervention effect on reading, with the total effect of 0.89 points (95% CI: 0.15 to 1.62) reduced to the natural direct effect of 0.40 points (95% CI: −0.48 to 1.28). Aerobic fitness did not mediate the effects on academic performance in the DWBH intervention. As aerobic fitness mediated the intervention effect on academic performance in one intervention, physical activity of an intensity that increases aerobic fitness is one strategy to improve academic performance among adolescents.

• Bjørnsen, Thomas; Wernbom, Mathias; Paulsen, Gøran; Markworth, James F.; Berntsen, Sveinung & D'Souza, Randall F. [Vis alle 8 forfattere av denne artikkelen] (2021). High-frequency blood flow-restricted resistance exercise results in acute and prolonged cellular stress more pronounced in type I than in type II fibers. Journal of applied physiology. ISSN 8750-7587. 131(2), s. 643–660. doi: 10.1152/japplphysiol.00115.2020. Fulltekst i vitenarkiv Vis sammendrag

  Myocellular stress with high-frequency blood flow-restricted resistance exercise (BFRRE) was investigated by measures of heat shock protein (HSP) responses, glycogen content, and inflammatory markers. Thirteen participants [age: 24 ± 2 yr (means ± SD), 9 males] completed two 5-day blocks of seven BFRRE sessions, separated by 10 days. Four sets of unilateral knee extensions to failure at 20% of one-repetition maximum (1RM) were performed. Muscle samples obtained before, 1 h after the first session in the first and second block (acute 1 and acute 2), after three sessions (day 4), during the “rest week,” and at 3 (post 3) and 10 days postintervention (post 10) were analyzed for HSP70, αB-crystallin, glycogen [periodic acid-Schiff (PAS) staining], mRNAs, miRNAs, and CD68+ (macrophages) and CD66b+ (neutrophils) cell numbers. αB-crystallin translocated from the cytosolic to the cytoskeletal fraction after acute 1 and acute 2 (P < 0.05) and immunostaining revealed larger responses in type I than in type II fibers (acute 1, 225 ± 184% vs. 92 ± 81%, respectively, P = 0.001). HSP70 was increased in the cytoskeletal fraction at day 4 and post 3, and immunostaining intensities were more elevated in type I than in type II fibers at day 4 (206 ± 84% vs. 72 ± 112%, respectively, P <0.001), during the rest week (98 ± 66% vs. 42 ± 79%, P < 0.001), and at post 3 (115 ± 82% vs. 28 ± 78%, P = 0.003). Glycogen content was reduced in both fiber types, but most pronounced in type I, which did not recover until the rest week (−15% to 29%, P ≤ 0.001). Intramuscular macrophage numbers were increased by ∼65% postintervention, but no changes were observed in muscle neutrophils. We conclude that high-frequency BFRRE with sets performed till failure stresses both fiber types, with type I fibers being most affected.

• Bjørnarå, Helga Birgit; Berntsen, Sveinung; Velde, Saskia J. te; Fyhri, Aslak; Isaksen, Ketil & Deforche, Benedicte [Vis alle 9 forfattere av denne artikkelen] (2021). The impact of weather conditions on everyday cycling with different bike types in parents of young children participating in the CARTOBIKE randomized controlled trial. International Journal of Sustainable Transportation. ISSN 1556-8318. doi: 10.1080/15568318.2021.1999538. Fulltekst i vitenarkiv Vis sammendrag

  Knowledge about how weather conditions affect travel behavior in different user groups and contexts is relevant for planners and policymakers to facilitate sustainable transportation systems. We aimed to assess the influence of day-to-day weather on cycling for transportation among parents of young children with access to different bike types (e-bike vs non e-bike) in a natural study setting over nine months. We hypothesized less impact of weather variability on cycling when using an e-bike compared with a non e-bike. A randomized, controlled trial was conducted in Southern Norway. The intervention group (n = 18) was in random order equipped with an e-bike with trailer for child transportation (n = 6), a cargo (longtail) bike (n = 6) and a traditional bike with trailer (n = 6), each for three months. These 18 participants reported cycling on 832 out of 3276 person-days (25%). We used dynamic structural equation modeling for intensive longitudinal data to examine the relations between daily weather conditions, bike type (e-bike vs traditional bike), and cycling (dichotomized daily at yes or no). Air temperature (positively) and wind speed (negatively) were both credible predictors of cycling, whereas the other predictors (precipitation in the morning (yes or no) and presence of snow (yes or no) were not. We added interaction terms between bike type and weather conditions, but none of the interaction terms had a credible effect on cycling. Thus, the relations between weather conditions and cycling were not moderated by bike type among parents of young children.

• Strandberg, Emelie; Bean, Christopher; Vassbakk-Svindland, Karianne; Brooke, Hannah L.; Sjövall, Katarina & Börjeson, Sussanne [Vis alle 9 forfattere av denne artikkelen] (2021). Who makes it all the way? Participants vs. decliners, and completers vs. drop-outs, in a 6-month exercise trial during cancer treatment. Results from the Phys-Can RCT. Supportive Care in Cancer. ISSN 0941-4355. 30, s. 1739–1748. doi: 10.1007/s00520-021-06576-0. Fulltekst i vitenarkiv Vis sammendrag

  Purpose To compare sociodemographic, health- and exercise-related characteristics of participants vs. decliners, and completers vs. drop-outs, in an exercise intervention trial during cancer treatment. Methods Patients with newly diagnosed breast, prostate, or colorectal cancer were invited to participate in a 6-month exercise intervention. Background data for all respondents (n=2051) were collected at baseline by questionnaire and medical records. Additional data were collected using an extended questionnaire, physical activity monitors, and ftness testing for trial participants (n=577). Moreover, a sub-group of decliners (n = 436) consented to additional data collection by an extended questionnaire . Data were analyzed for between-group diferences using independent t-tests and chi2 -tests. Results Trial participants were younger (59±12yrs vs. 64±11yrs, p<.001), more likely to be women (80% vs. 75%, p=.012), and scheduled for chemotherapy treatment (54% vs. 34%, p<.001), compared to decliners (n=1391). A greater proportion had university education (60% vs 40%, p<.001), reported higher anxiety and fatigue, higher exercise self-efcacy and outcome expectations, and less kinesiophobia at baseline compared to decliners. A greater proportion of trial participants were classifed as ‘not physically active’ at baseline; however, within the group who participated, being “physically active” at baseline was associated with trial completion. Completers (n=410) also reported less kinesiophobia than drop-outs (n=167). Conclusion The recruitment procedures used in comprehensive oncology exercise trials should specifcally address barriers for participation among men, patients without university education and older patients. Individualized eforts should be made to enroll patients with low exercise self-efcacy and low outcome expectations of exercise. To retain participants in an ongoing exercise intervention, extra support may be needed for patients with kinesiophobia and those lacking healthenhancing exercise habits at baseline.

• Vistad, Ingvild; Skorstad, Mette; Demmelmaier, Ingrid; Småstuen, Milada Cvancarova; Lindemann, Kristina Yvonne Kathe & Wisløff, Torbjørn [Vis alle 8 forfattere av denne artikkelen] (2021). Lifestyle and Empowerment Techniques in Survivorship of Gynaecologic Oncology (LETSGO study): A study protocol for a multicentre longitudinal interventional study using mobile health technology and biobanking. BMJ Open. 11(7). doi: 10.1136/bmjopen-2021-050930. Fulltekst i vitenarkiv Vis sammendrag

  Introduction The number of gynaecological cancer survivors is increasing and there is a need for a more sustainable model of follow-up care. Today’s follow-up model is time-consuming and patients have reported unmet needs regarding information about their cancer and strategies for managing the consequences of treatment. The main aim of this study is to assess health-related empowerment—in terms of patient education, psychosocial support, and promotion of physical activity—in a new follow-up model by comparing it to standard follow-up in a quasi-randomised study involving intervention hospitals and control hospitals. Methods and analysis At the intervention hospitals, patients will be stratified by risk of recurrence and late effects to either 1 or 3 years’ follow-up. Nurses will replace doctors in half of the follow-up visits and focus in particular on patient education, self-management and physical activity. They will provide patients with information and guide them in goal setting and action planning. These measures will be reinforced by a smartphone application for monitoring symptoms and promoting physical activity. At the control hospitals, patients will be included in the standard follow-up programme. All patients will be asked to complete questionnaires at baseline and after 3, 6, 12, 24 and 36 months. Blood samples will be collected for biobanking at 3, 12 and 36 months. The primary outcome is health-related empowerment. Secondary outcomes include health-related quality of life, adherence to physical activity recommendations, time to recurrence, healthcare costs and changes in biomarkers. Changes in these outcomes will be analysed using generalised linear mixed models for repeated measures. Type of hospital (intervention or control), time (measurement point), and possible confounders will be included as fixed factors. Ethics and dissemination The study is approved by the Regional Committee for Medical Research Ethics (2019/11093). Dissemination of findings will occur at the local, national and international levels.

• Mazzoni, Anne-Sophie; Brooke, Hannah L.; Berntsen, Sveinung; Nordin, Karin & Demmelmaier, Ingrid (2021). Effect of self-regulatory behaviour change techniques and predictors of physical activity maintenance in cancer survivors: a 12-month follow-up of the Phys-Can RCT. BMC Cancer. 21(1), s. 1–12. doi: 10.1186/s12885-021-08996-x. Fulltekst i vitenarkiv
• Bjørnarå, Helga Birgit; Westergren, Thomas; Sejersted, Ellen; Torstveit, Monica Klungland; Hansen, Bjørge Hermann & Berntsen, Sveinung [Vis alle 7 forfattere av denne artikkelen] (2021). Does organized sports participation in childhood and adolescence positively influence health? A review of reviews. Preventive Medicine Reports. 23. doi: 10.1016/j.pmedr.2021.101425. Fulltekst i vitenarkiv
• Mackintosh, Kelly A.; McNarry, Melitta A.; Berntsen, Sveinung; Steele, James; Sejersted, Ellen & Westergren, Thomas (2021). Physical activity and sedentary time in children and adolescents with asthma: A systematic review and meta‐analysis. Scandinavian Journal of Medicine & Science in Sports. ISSN 0905-7188. 31(6), s. 1183–1195. doi: 10.1111/sms.13937. Fulltekst i vitenarkiv
• Nunavath, Vimala; Johansen, Sahand; Johannessen, Tommy Sandtorv; Jiao, Lei; Hansen, Bjørge Hermann & Berntsen, Sveinung [Vis alle 7 forfattere av denne artikkelen] (2021). Deep Learning for Classifying Physical Activities from Accelerometer Data. Sensors. 21(16). doi: 10.3390/s21165564. Fulltekst i vitenarkiv Vis sammendrag

  Physical inactivity increases the risk of many adverse health conditions, including the world’s major non-communicable diseases, such as coronary heart disease, type 2 diabetes, and breast and colon cancers, shortening life expectancy. There are minimal medical care and personal trainers’ methods to monitor a patient’s actual physical activity types. To improve activity monitoring, we propose an artificial-intelligence-based approach to classify physical movement activity patterns. In more detail, we employ two deep learning (DL) methods, namely a deep feed-forward neural network (DNN) and a deep recurrent neural network (RNN) for this purpose. We evaluate the two models on two physical movement datasets collected from several volunteers who carried tri-axial accelerometer sensors. The first dataset is from the UCI machine learning repository, which contains 14 different activities-of-daily-life (ADL) and is collected from 16 volunteers who carried a single wrist-worn tri-axial accelerometer. The second dataset includes ten other ADLs and is gathered from eight volunteers who placed the sensors on their hips. Our experiment results show that the RNN model provides accurate performance compared to the state-of-the-art methods in classifying the fundamental movement patterns with an overall accuracy of 84.89% and an overall F1-score of 82.56%. The results indicate that our method provides the medical doctors and trainers a promising way to track and understand a patient’s physical activities precisely for better treatment.

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• Torstveit, Monica Klungland; Lohne-Seiler, Hilde; Berntsen, Sveinung & Anderssen, Sigmund Alfred (2026). Fysisk aktivitet og helse – fra begrepsforståelse til implementering av kunnskap. Cappelen Damm Akademisk. ISBN 9788202806040. 468 s. Fulltekst i vitenarkiv

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• Berntsen, Sveinung (2026). Effekt av naturbasert rehabilitering for unge kreftoverlevere. Fulltekst i vitenarkiv Vis sammendrag

  Faggruppen for barne- og ungdomsfysioterapi i Norsk fysioterapeutforbund ønsker velkommen til årlig Kongress og årsmøte Vi møtes på Radisson Blue Caledonien Hotel, Kristiansand. 11. - 13. mars 2026 for tre dager med faglig påfyll, inspirasjon og hyggelig samvær med engasjerte fysioterapeuter

• Feron, Jack; Rahman, Foyzul; Fosstveit, Sindre Herskedal; Joyce, Kelsey E.; Lohne-Seiler, Hilde & Berntsen, Sveinung [Vis alle 9 forfattere av denne artikkelen] (2025). Accelerometer derived physical activity behaviors and cerebral hemodynamics in older adults. Fulltekst i vitenarkiv
• Fosstveit, Sindre Herskedal; Vistad, Ingvild; Larsen, Torill Marie Bogsnes; Lohne-Seiler, Hilde & Berntsen, Sveinung (2025). Assessing the Needs and Potential of a Motivational App to Support Cancer Survivors in Physical Activity Participation. Fulltekst i vitenarkiv
• Lohne-Seiler, Hilde; Fosstveit, Sindre Herskedal; Feron, Jack; Joyce, Kelsey E.; Segaert, Katrien & Lucas, Samual J.E. [Vis alle 7 forfattere av denne artikkelen] (2025). The impact of home-based high- intensity interval training on physical function in healthy older adults. Fulltekst i vitenarkiv Vis sammendrag

  INTRODUCTION: Resistance training is widely recommended to enhance physical function (PF) in older adults (1). High-velocity resistance training receives particular attention due to the strong link between muscular power and functional movement (2). High-intensity interval training (HIIT) has also shown promise for improving power-related adaptations in older populations (3). As a time-efficient and generally well-tolerated training modality, HIIT offers a viable exercise option for older adults (4). However, its efficacy in enhancing PF among this population remains unclear. Furthermore, the effectiveness of HIIT under free-living conditions as part of broader public health strategies has not been adequately investigated (5). Therefore, the present study aimed to assess the impact of a 6-month home-based HIIT program on PF in healthy older adults. METHOD: Healthy older adults (n=233, aged 60-84, 54% female) from Norway and the UK were randomly assigned to either a HIIT group (mean age±SD: 67.6±5.9yr) or a non-exercising control group (mean age±SD: 67.0±5.2yr). The exercising group participated in a 6-month, thrice weekly HIIT intervention (2 interval and 1 circuit sessions per week). PF measures at pre- and post-intervention included Grip strength, 30-sec-chair-stand, Chair-sit-and-reach, Back scratch, Timed-up-and-go, and One-leg standing. Additionally, PF was calculated as a composite Z-score (PF Z-score) based on all aforementioned tests. General Linear Models were used to assess between-group differences in post-intervention scores for each standardized test and the PF Z-score, with pre-intervention scores, age, sex, and country of residence as covariates, and group as a fixed factor. Effect sizes (ES) were calculated using mean differences (pre-post), pooled standard deviations, and sample sizes for the exercise and control groups. Alpha level of 5% was chosen for statistical significance, with 95% CI presented. RESULTS: Significant between-group differences at post-intervention were observed for PF Z-score (β=0.24, [95%CI: 0.17;0.30] (ES:0.97), Grip-strength (β=1.8 [0.8;2.8] kg (ES:0.48), 30-sec-chair-stand (β=1.3 [0.7; 1.8] repetitions (ES: 0.63), Back scratch (β=2.1 [0.8;3.5] cm (ES:0.43), and Timed-up-and-go (β=−0.3 [−0.4;−0.2] seconds (ES:0.71). No significant between-group differences post-intervention were observed for Chair-sit-and-reach and One-leg standing tests. CONCLUSION: These findings indicate that healthy older adults can enhance their PF through a 6-month home-based HIIT intervention. However, no significant effects were observed in joint flexibility of the lower extremities or static balance ability. Nonetheless, these findings reinforce the potential of HIIT as a valuable component in public health strategies for promoting physical function in healthy older adults. REFERENCES: 1. Fragala et al., J Strength Cond Res, 2019 2. Schaun et al., Exp Gerontol, 2021 3. Herrod et al., GeroScience, 2021 4. Marriott et al., Sports Medicine Open, 2021 5. Gray et al., BJSM, 2016

• Fosstveit, Sindre Herskedal & Berntsen, Sveinung (2025). Assessing the Needs and Potential of a Motivational App to Support Cancer Survivors in Physical Activity Engagement. Fulltekst i vitenarkiv
• Lohne-Seiler, Hilde & Berntsen, Sveinung (2025). The Impact of High-Intensity Interval Training on Physical Function in Healthy Older Adults. Fulltekst i vitenarkiv
• Wiestad, Tor Helge & Berntsen, Sveinung (2025). High-intensity exercise during chemotherapy preserves cardiorespiratory fitness in breast cancer patients. Fulltekst i vitenarkiv
• Vistad, Ingvild; Skorstad, Mette; Hagen, Milada; Demmelmaier, Ingrid; Bjørge, Line & Poll-Franse, Lonneke V. Van De [Vis alle 12 forfattere av denne artikkelen] (2025). The Impact Of The LETSGO Personalized Follow-Up Model On Empowerment And Quality Of Life In Gynaecological Cancer Survivors: A Multicenter Quasi-Experimental Study. International Journal of Gynecological Cancer. ISSN 1048-891X. 35(2). doi: 10.1016/j.ijgc.2024.100110. Fulltekst i vitenarkiv Vis sammendrag

  Background: Increasing outpatient demands and unmet patient needs necessitate personalized follow‐up care for cancer survivors. This study investigated whether a self‐management–focused follow‐up model improves empowerment and quality of life (QoL) in gynecological cancer survivors compared to standard follow‐up. Methods: Twelve Norwegian hospitals participated in this cohort study. Patients initiating routine follow‐up after primary treatment were eligible and allocated to either intervention or standard care follow‐up groups based on their treatment hospital. The intervention included nurse‐led consultations using coaching techniques for education on symptom monitoring and healthy lifestyle, alternated with physician‐led consultations and access to a mobile app. Standard follow‐up consisted of physician‐led consultations only. The primary outcome was change in patient empowerment over 12 months, measured with the self‐monitoring and insight domain of the Health Education Impact Questionnaire (heiQ). Secondary outcomes included changes in remaining heiQ domains and QoL. Data were analyzed according to intention‐to‐treat principles using linear mixed effects models. Results: Among 741 participants (intervention: 378, standard: 363), baseline characteristics were comparable. At 12 months, no significant differences were observed in self‐monitoring and insight (Δ = 0.02 [95% confidence interval (CI), –0.04 to 0.08]; effect sizes [ES] = 0.29). However, health‐directed activity (Δ = 0.15 [95% CI, 0.04– 0.25]; ES = 0.15), emotional well‐being (Δ = 0.12 [95% CI, 0.02–0.20]; ES = 0.15), social functioning (Δ = 5.2 [95% CI, 1.1–9.3]; ES = 0.41), and physical functioning (Δ = 2.5 [95% CI, 0.0–5.0]; ES = 0.20) were significantly more improved in the intervention group. Conclusion: Lifestyle and Empowerment Techniques in Survivorship of Gynaecologic Oncology follow‐up did not significantly impact self‐monitoring and insight, but positively influenced other survivorship domains, indicating its potential for enhancing self‐management and QoL in gynecological cancer survivors.

• Lohne-Seiler, Hilde & Berntsen, Sveinung (2024). Symposium “Healthy Aging: What is important for a good life as elderly?”. Fulltekst i vitenarkiv
• Wiestad, Helge; Vikmoen, Olav; Ranes, Maria; Thormodsen, Inger; Fluge, Øystein & Mella, Olav [Vis alle 9 forfattere av denne artikkelen] (2024). EFFECTS OF HIGH VS. MODERATE INTENSITY EXERCISE DURING (NEO-)ADJUVANT CHEMOTHERAPY ON CARDIORESPIRA- TORY FITNESS, MITOCHONDRIAL ENZYMES AND CAPILLARIES IN WOMEN WITH BREAST CANCER. Fulltekst i vitenarkiv
• Fernandes, Eunice Gomes; Fosstveit, Sindre Herskedal; Feron, Jack; Rahman, Foyzul; Lucas, Samuel J.E. & Lohne-Seiler, Hilde [Vis alle 10 forfattere av denne artikkelen] (2024). Exercise training speeds language comprehension for monolingual but not bilingual older adults: evidence from a randomised controlled trial. Fulltekst i vitenarkiv
• Vikmoen, Olav; Wiestad, Tor Helge; Thormodsen, Inger; Nordin, Karin; Berntsen, Sveinung & Demmelmaier, Ingrid [Vis alle 8 forfattere av denne artikkelen] (2024). EFFECTS OF HIGH AND LOW-TO-MODERATE INTENSITY EXERCISE DURING (NEO-)ADJUVANT CHEMOTHERAPY ON MUS- CLE STRENGTH, BODY COMPOSITION, MUSCLE FIBER SIZE, MYONUCLEAR CONTENT AND SATELLITE CELL NUMBER. Fulltekst i vitenarkiv
• Fosstveit, Sindre Herskedal; Lohne-Seiler, Hilde; Feron, Jack; Joyce, Kelsey; Segaert, Katrien & Lucas, Samuel J.E. [Vis alle 7 forfattere av denne artikkelen] (2024). Enhancing cardiorespiratory fitness in older adults – HIIT at Home, a randomised controlled trial. Fulltekst i vitenarkiv
• Lohne-Seiler, Hilde & Berntsen, Sveinung (2024). Healthy Aging: “What is important for a good life as elderly?”. Fulltekst i vitenarkiv
• Lohne-Seiler, Hilde; Fosstveit, Sindre Herskedal; Feron, Jack; Joyce, Kelsey; Segaert, Katrien & Lucas, Samuel J. E. [Vis alle 7 forfattere av denne artikkelen] (2024). HIIT at home – Enhancing physical function and health-related quality of life in older adults. Any associations? Fulltekst i vitenarkiv
• Feron, Jack; Rahman, Foyzul; Fosstveit, Sindre Herskedal; Joyce, Kelsey; Gilani, Ahmed & Lohne-Seiler, Hilde [Vis alle 10 forfattere av denne artikkelen] (2024). Cerebral blood flow and arterial transit time responses to home-based exercise training in healthy older adults. Fulltekst i vitenarkiv
• Fosstveit, Sindre Herskedal; Berntsen, Sveinung; Feron, Jack; Joyce, Kelsey; Ivarsson, Andreas & Segaert, Katrien [Vis alle 8 forfattere av denne artikkelen] (2024). Sticking to It: High Adherence Levels and Enhanced Cardiorespiratory Fitness in Older Adults Performing Home-Based HIIT. Fulltekst i vitenarkiv
• Feron, Jack; Rahman, Foyzul; Fosstveit, Sindre Herskedal; Joyce, Kelsey; Gilani, Ahmed & Lohne-Seiler, Hilde [Vis alle 10 forfattere av denne artikkelen] (2024). Cerebral blood flow and arterial transit time responses to home-based exercise training in healthy older adults. Fulltekst i vitenarkiv
• Rahman, Foyzul; Tsvetanov, Kamen; Feron, Jack; Mullinger, Karen; Joyce, Kelsey & Gilani, Ahmed [Vis alle 14 forfattere av denne artikkelen] (2024). Explaining age-related word-finding failures using neural and lifestyle measures, and the effect of an exercise intervention and bilingualism on non-linguistic cognitive function. Fulltekst i vitenarkiv
• Fernandes, Eunice Gomes; Fosstveit, Sindre Herskedal; Feron, Jack; Rahman, Foyzul; Lucas, Samuel J.E. & Lohne-Seiler, Hilde [Vis alle 10 forfattere av denne artikkelen] (2024). Effects of exercise training on language comprehension in monolingual and bilingual older adults: A randomized controlled trial. Fulltekst i vitenarkiv
• Fosstveit, Sindre Herskedal; Lohne-Seiler, Hilde; Feron, Jack; Lucas, Samuel J.E. & Berntsen, Sveinung (2023). HOW DOES OLDER ADULTS’ FITNESS LEVEL IMPACT THE ASSOCIATIONS BETWEEN BORGS RPE SCALE AND PHYSIOLOGICAL MEASURES OF EXERCISE INTENSITY? Fulltekst i vitenarkiv
• Malnes, Lena; Berntsen, Sveinung; Kolle, Elin; Ivarsson, Andreas & Dyrstad, Sindre Mikal (2023). School-based physical activity in relation to active travel among adolescents. Fulltekst i vitenarkiv
• Henriksson, Anna; Stenling, Andreas; Mazzoni, Anne-Sophie; Sjövall, Katarina; Börjeson, Sussanne & Buffart, Laurien M [Vis alle 10 forfattere av denne artikkelen] (2023). Exercise adherence trajectory during chemotherapy treatment in patients with breast cancer- Results from the Phys-Can study. Fulltekst i vitenarkiv
• Vikmoen, Olav; Strandberg, Emelie; Demmelmaier, Ingrid; Berntsen, Sveinung; Nordin, Karin & Raastad, Truls (2023). EFFECTS OF HEAVY-LOAD STRENGTH TRAINING DURING (NEO-)ADJUVANT CHEMOTHERAPY ON CARDIORESPIRATORY FITNESS, MITOCHONDRIAL ENZYMES AND CAPILLARIES IN WOMEN WITH BREAST CANCER. Fulltekst i vitenarkiv
• Western, Benedikte; Ivarsson, Andreas; Demmelmaier, Ingrid; Vistad, Ingvild; Berntsen, Sveinung & Buffart, Laurien M. (2023). SUGGESTED TARGETS FOR IMPROVING EXERCISE INTERVENTION COMPLETION IN CANCER PATIENTS – AN INDIVIDUAL PATIENT DATA META-ANALYSIS FROM THE POLARIS STUDY. Fulltekst i vitenarkiv
• Mazzoni, Anne-Sophie; Strandberg, Emelie; Börjeson, Susanne; Sjövall, Katarina; Berntsen, Sveinung & Demmelmaier, Ingrid [Vis alle 7 forfattere av denne artikkelen] (2023). Reallocating sedentary time to physical activity may have beneficial effects on fatigue in patients with breast cancer: findings from the Phys-Can project. Fulltekst i vitenarkiv
• Wiestad, Tor Helge; Vikmoen, Olav; Ranes, Maria; Thormodsen, Inger; Fluge, Øystein & Mella, Olav [Vis alle 9 forfattere av denne artikkelen] (2023). EFFECTS OF HIGH VS. MODERATE INTENSITY COMBINED STRENGTH AND ENDURANCE TRAINING DURING CHEMOTHERAPY ON CARDIORESPIRATORY FITNESS, MUSCLE STRENGTH AND ENDURANCE IN WOMEN WITH BREAST CANCER. Fulltekst i vitenarkiv
• Spencer, Matthew; Aasland, Erik; Hansen, Bjørge Hermann & Berntsen, Sveinung (2023). Hva vil du lese om i Vitensporten? Fulltekst i vitenarkiv
• Fosstveit, Sindre Herskedal; Seiler, Hilde Lohne; Feron, Jack; Lucas, Samuel J. E. & Berntsen, Sveinung (2023). How does older adults’ fitness level impact the associations between Borg's RPE scale and physiological measures of exercise intensity? Fulltekst i vitenarkiv
• Feron, Jack; Rahman, F.; Fosstveit, Sindre Herskedal; Joyce, Kelsey; Gilani, Ahmed & Seiler, Hilde Lohne [Vis alle 10 forfattere av denne artikkelen] (2023). Determinants of resting cerebral blood flow and arterial transit time in healthy older adults. Fulltekst i vitenarkiv
• Mazzoni, Anne-Sophie; Börjeson, Sussanne; Sjövall, Katarina; Berntsen, Sveinung & Nordin, Karin (2023). The role of long-term physical activity in relation to cancer-related health outcomes: a 12-month follow-up of an exercise intervention. Fulltekst i vitenarkiv
• Feron, Jack; Rahman, F.; Fosstveit, Sindre Herskedal; Joyce, K; Giliani, A & Lohne-Seiler, Hilde [Vis alle 10 forfattere av denne artikkelen] (2023). DETERMINANTS OF RESTING CEREBRAL BLOOD FLOW AND ARTERIAL TRANSIT TIME IN HEALTHY OLDER ADULTS. Fulltekst i vitenarkiv
• Fosstveit, Sindre Herskedal; Feron, Jack; Lucas, Samuel J.E.; Seiler, Hilde Lohne & Berntsen, Sveinung (2023). How does older adults’ fitness level impact the associations between Borg's RPE scale and physiological measures of exercise intensity? Fulltekst i vitenarkiv
• Bjørnsen, Thomas; Hody, Stephanie; Raastad, Truls; Paulsen, Gøran; Wernbom, Mathias & Vårvik, Fredrik Tonstad [Vis alle 8 forfattere av denne artikkelen] (2022). High-Frequency Blood Flow Restricted Resistance Exercise To Failure Induces Higher Cellular Stress In Muscle Fibres Than A Non-Failure Protocol. Fulltekst i vitenarkiv
• Berntsen, Sveinung; Demmelmaier, Ingrid & Vistad, Ingvild (2022). Sufficiently active based on what? Fulltekst i vitenarkiv
• Fosstveit, Sindre Herskedal; Lindberg, Kolbjørn Andreas; Bjørnsen, Thomas; Vårvik, Fredrik Tonstad; Berntsen, Sveinung & Seiler, Hilde Lohne (2022). Associations between power training-induced changes in body composition and physical function in older men: a pretest-posttest experimental study. Fulltekst i vitenarkiv
• Berntsen, Sveinung (2022). Trening ved kreftsykdom, viktigere enn tradisjonell behandling? Fulltekst i vitenarkiv
• Berntsen, Sveinung (2022). Esport - et verktøy for læring og dannelse. Fulltekst i vitenarkiv
• Bjørnsen, Thomas & Berntsen, Sveinung (2022). Så lite skal til for å bli sterkere. lokalavisen fedrelandsvennen. Fulltekst i vitenarkiv
• Lohne-Seiler, Hilde; Lindberg, Kolbjørn Andreas; Fosstveit, Sindre Herskedal; Sibayan, Erlend E.; Fjeller, Joachim S. & Løvold, Sondre [Vis alle 11 forfattere av denne artikkelen] (2022). Physical function and health-related quality of life in older men after 10-weeks power training – any associations? Fulltekst i vitenarkiv
• Fosstveit, Sindre Herskedal; Lindberg, Kolbjørn Andreas; Bjørnsen, Thomas; Sibayan, Erlend E.; Fjeller, Joachim S. & Løvold, Sondre [Vis alle 10 forfattere av denne artikkelen] (2022). Associations between power training-induced changes in body composition and physical function in older men: a pretest-posttest experimental study. Fulltekst i vitenarkiv
• Berntsen, Sveinung (2022). Penger til fysisk aktivitet kan lønne seg. lokalavisen fedrelandsvennen. Fulltekst i vitenarkiv
• Berntsen, Sveinung & Torstveit, Monica Klungland (2021). Ser til Island for å forbedre den norske idrettsmodellen. [Journal]. Aftenposten. Fulltekst i vitenarkiv
• Berntsen, Sveinung (2021). Kreft og trening: Gode gevinster. Fulltekst i vitenarkiv
• Berntsen, Sveinung (2021). Kreft og trening: Gode gevinster. Fulltekst i vitenarkiv
• Berntsen, Sveinung (2021). Kreft og trening: Gode gevinster. Fulltekst i vitenarkiv
• Berntsen, Sveinung (2021). Kreft og trening: Gode gevinster. Fulltekst i vitenarkiv
• Berntsen, Sveinung (2021). Fysisk aktivitet og trening under kreftbehandling: Hva, hvordan og hvorfor? Fulltekst i vitenarkiv
• Berntsen, Sveinung (2021). Ser til Island for å forbedre den norske idrettsmodellen. [Journal]. fvn.no. Fulltekst i vitenarkiv
• Berntsen, Sveinung (2021). Universitetet i Agder knytter seg tettere til lokal sport og idrett. [Internet]. idrett-anlegg.no. Fulltekst i vitenarkiv
• Berntsen, Sveinung & Breivik, Gunnar (2021). Dette er Vitensporten. Fulltekst i vitenarkiv

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