Kari Hansen Berg

• Berg, Kari Hansen; Rohde, Gudrun Elin; Pripp, Are Hugo; Prøven, Anne; Benestad, Espen Esther Pirelli & Østensen, Monika Elisabeth [Vis alle 7 forfattere av denne artikkelen] (2021). Increased proportion of comorbidities but no deterioration of sexual quality of life during a 5-year follow-up in patients with axial spondyloarthritis in the biologic treatment era. Rheumatology. ISSN 1462-0324. 60(9), s. 4112–4120. doi: 10.1093/rheumatology/keaa887. Fulltekst i vitenarkiv
• Rohde, Gudrun E.; Berg, Kari Ellen; Pripp, Are Hugo; Prøven, Anne & Haugeberg, Glenn (2020). No deterioration in health-related quality of life in patients with axial spondyloarthritis followed for 5 years in ordinary outpatient clinics in the biological treatment era. Quality of Life Research. ISSN 0962-9343. 29(1), s. 99–107. doi: 10.1007/s11136-019-02308-4. Fulltekst i vitenarkiv Vis sammendrag

  Background: Axial spondyloarthritis (ax-SpA) causes pain, fatigue, stiffness, loss of physical function and impaired health-related quality of life (HRQOL). Aims: The study aimed to explore the changes in HRQOL over 5 years in patients with ax-SpA and to identify baseline predictors associated with changes in HRQOL assessed using three HRQOL measures. Methods: Demographic, disease, medication and HRQOL data were collected at baseline and at 5-year follow-up. HRQOL was assessed using SF-6D, 15D and SF-36. Analyses involved McNemar, independent paired t tests and multiple regression. Results: In the 240 (women 31%, men 69%) ax-SpA patients assessed (mean age 46 years), measures reflecting disease activity decreased and co-morbidities increased, and more patients were treated with biologic drugs during follow-up. No deterioration in HRQOL was observed between baseline and 5-year follow-up; indeed, there was a significant increase in SF-6D and SF-36 PCS scores. Improvement in HRQOL measured by SF-6D was associated with younger age, higher education, low Bath Ankylosing Spondylitis (BAS) Activity Index (BASDAI), high BAS Patient Global Score and high C-reactive protein; improvement in SF-36 PCS was associated with younger age, higher education, low BASDAI and no use of biological treatment at baseline. Conclusion: Our ax-SpA outpatient clinic patients, with more patients treated with biologic drugs during the 5-year follow-up, did not deteriorate in HRQOL. In fact, the physical dimension in HRQOL improved over the years, as did measures reflecting disease activity. Our study adds evidence to the importance of suppressing inflammation to maintain and improve HRQOL in ax-SpA patients.

• Berg, Kari Hansen; Rohde, Gudrun E.; Prøven, Anne; Benestad, Esben Esther Pirelli; Østensen, Monika Elisabeth & Haugeberg, Glenn (2019). Sexual Quality of Life in Patients with Axial Spondyloarthritis in the Biologic Treatment Era. Journal of Rheumatology. ISSN 0315-162X. 46(9), s. 1075–1083. doi: 10.3899/jrheum.180413. Fulltekst i vitenarkiv Vis sammendrag

  Objective. To examine the relationship between demographics, disease-related variables, treatment, and sexual quality of life (SQOL) in men and women with axial spondyloarthritis (axSpA). Methods. AxSpA patients were consecutively recruited from 2 rheumatology outpatient clinics in southern Norway. A broad spectrum of demographics, disease, treatment, and QOL data were systematically collected. SQOL was assessed using the SQOL-Female (SQOL-F) questionnaire (score range 18–108). Appropriate statistical tests were applied for group comparison, and the association between independent variables and SQOL-F was examined using multiple linear regression analysis. Results. A total of 360 (240 men, 120 women) axSpA patients with mean age 45.5 years and disease duration 13.9 years were included. Seventy-eight percent were married/cohabiting, 26.7% were current smokers, 71.0% were employed, 86.0% performed > 1-h exercise per week, and 88.0% were HLA-B27–positive. Mean (SD) values for disease measures were C-reactive protein (CRP) 8.5 (12.1) mg/l, Bath Ankylosing Spondylitis Disease Activity Index 3.1 (2.1), Bath Ankylosing Spondylitis Global Score (BAS-G) 3.8 (2.5), Bath Ankylosing Spondylitis Functional Index 2.7 (2.2), and Health Assessment Questionnaire 0.6 (0.5). The proportion of patients using nonsteroidal antiinflammatory drugs was 44.0%, synthetic disease-modifying antirheumatic drugs (DMARD) 5.0%, and biologic DMARD 24.0%. Mean (SD) total sum score for SQOL was 76.6 (11.3). In multivariate analysis, female sex, increased body mass index, measures reflecting disease activity (BAS-G and CRP), and current biologic treatment were independently associated with a lower SQOL. Conclusion. Our data suggest that inflammation in patients with axSpA even in the biologic treatment era reduces SQOL.

• Rohde, Gudrun E.; Berg, Kari Ellen; Prøven, Anne & Haugeberg, Glenn (2017). The relationship between demographic- and disease-related variables and health-related quality of life in patients with axial spondyloarthritis. BMC Musculoskeletal Disorders. ISSN 1471-2474. 18(1). doi: 10.1186/s12891-017-1693-z. Fulltekst i vitenarkiv
• Berg, Kari Ellen; Rohde, Gudrun E.; Prøven, Anne; Almås, Elsa Mari; Benestad, Esben Esther Pirelli & Østensen, Monika Elisabeth [Vis alle 7 forfattere av denne artikkelen] (2017). Exploring the relationship between demographic and disease-related variables and perceived effect of health status on sexual activity in patients with axial spondyloarthritis: associations found only with non-disease variables. Scandinavian Journal of Rheumatology. ISSN 0300-9742. 46(6), s. 461–467. doi: 10.1080/03009742.2017.1279684.
• Rohde, Gudrun-Elin; Berg, Kari Ellen & Haugeberg, Glenn (2014). Perceived effects of health status on sexual activity in women and men older than 50 years. Health and Quality of Life Outcomes. ISSN 1477-7525. 12(1). doi: 10.1186/1477-7525-12-43.

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• Berg, Kari Ellen; Rohde, Gudrun E.; Pripp, Are Hugo; Prøven, Anne & Haugeberg, Glenn (2019). No changes in sexual quality of life over a 5-years period in patients with axial spondyloarthritis. Quality of Life Research. ISSN 0962-9343. 28, s. S114–S114.
• Berg, Kari Ellen (2022). Sexual quality of life in patients with axial spondyloarthritis. University of Agder. ISSN 978-82-8427-088-3. Fulltekst i vitenarkiv

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