Fitness, Ageing and Bilingualism (FAB)

• Prystauka, Yanina; Rahman, Foyzul; Busby, Natalie; Roeser, Jens; Boraxbekk, Carl-Johan & Feron, Jack [Vis alle 11 forfattere av denne artikkelen] (2025). Assessing the Utility of Predicted Brain Age for Explaining Variability in Language Abilities in Healthy Older Adults. Neurobiology of Language (NoL). 6. doi: 10.1162/nol.a.21. Fulltekst i vitenarkiv Vis sammendrag

  We investigated whether the difference between chronological and modeled brain age explains individual differences in language performance among healthy older adults. Age-related decline in language abilities is widely documented, with considerable variability among healthy older individuals in both language performance and underlying neural substrate. We derived predicted brain age from grey and white matter using machine learning and used this measure to estimate neurological deviations from chronological age. Using Bayesian mixed-effects modeling, we tested whether brain-age deviations predict language performance in a sample of 86 adults aged 60 years and above. We assessed the effect of brain-age deviations on performance across four well-established language processing tasks, each tapping into linguistic domains known to be vulnerable to ageing and show individual variability in skill levels, in both comprehension and production. Our findings suggest that, in healthy older individuals, predicted deviations of brain age from chronological age do not predict language abilities. This challenges the idea that brain age is a reliable determinant of language processing variability, at least in healthy (as opposed to pathological) ageing and highlights the need to consider other neural and cognitive factors when studying language decline.

• Rahman, Foyzul; Tsvetanov, Kamen A.; Feron, Jack; Mullinger, Karen; Joyce, Kelsey & Gilani, Ahmed [Vis alle 11 forfattere av denne artikkelen] (2025). Explaining tip-of-the-tongue experiences in older adults: The role of brain-based and cardiorespiratory fitness factors. Neurobiology of Aging. ISSN 0197-4580. doi: 10.1016/j.neurobiolaging.2025.06.008. Fulltekst i vitenarkiv
• Feron, Jack; Rahman, Foyzul; Fosstveit, Sindre Herskedal; Joyce, Kelsey E; Gilani, Ahmed & Lohne-Seiler, Hilde [Vis alle 10 forfattere av denne artikkelen] (2024). Cerebral blood flow and arterial transit time responses to exercise training in older adults. NeuroImage. ISSN 1053-8119. 303. doi: 10.1016/j.neuroimage.2024.120919. Fulltekst i vitenarkiv
• Fernandes, Eunice Gomes; Segaert, Katrien; Rahman, Foyzul; Wetterlin, Allison Louise & Wheeldon, Linda Ruth (2024). Bilingualism and ageing independently impact on language processing: evidence from comprehension and production. Bilingualism: Language and Cognition. ISSN 1366-7289. doi: 10.1017/S1366728924000245. Fulltekst i vitenarkiv

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• Feron, Jack; Rahman, Foyzul; Fosstveit, Sindre Herskedal; Joyce, Kelsey E.; Lohne-Seiler, Hilde & Berntsen, Sveinung [Vis alle 9 forfattere av denne artikkelen] (2025). Accelerometer derived physical activity behaviors and cerebral hemodynamics in older adults. Fulltekst i vitenarkiv
• Lohne-Seiler, Hilde; Fosstveit, Sindre Herskedal; Feron, Jack; Joyce, Kelsey E.; Segaert, Katrien & Lucas, Samual J.E. [Vis alle 7 forfattere av denne artikkelen] (2025). The impact of home-based high- intensity interval training on physical function in healthy older adults. Fulltekst i vitenarkiv Vis sammendrag

  INTRODUCTION: Resistance training is widely recommended to enhance physical function (PF) in older adults (1). High-velocity resistance training receives particular attention due to the strong link between muscular power and functional movement (2). High-intensity interval training (HIIT) has also shown promise for improving power-related adaptations in older populations (3). As a time-efficient and generally well-tolerated training modality, HIIT offers a viable exercise option for older adults (4). However, its efficacy in enhancing PF among this population remains unclear. Furthermore, the effectiveness of HIIT under free-living conditions as part of broader public health strategies has not been adequately investigated (5). Therefore, the present study aimed to assess the impact of a 6-month home-based HIIT program on PF in healthy older adults. METHOD: Healthy older adults (n=233, aged 60-84, 54% female) from Norway and the UK were randomly assigned to either a HIIT group (mean age±SD: 67.6±5.9yr) or a non-exercising control group (mean age±SD: 67.0±5.2yr). The exercising group participated in a 6-month, thrice weekly HIIT intervention (2 interval and 1 circuit sessions per week). PF measures at pre- and post-intervention included Grip strength, 30-sec-chair-stand, Chair-sit-and-reach, Back scratch, Timed-up-and-go, and One-leg standing. Additionally, PF was calculated as a composite Z-score (PF Z-score) based on all aforementioned tests. General Linear Models were used to assess between-group differences in post-intervention scores for each standardized test and the PF Z-score, with pre-intervention scores, age, sex, and country of residence as covariates, and group as a fixed factor. Effect sizes (ES) were calculated using mean differences (pre-post), pooled standard deviations, and sample sizes for the exercise and control groups. Alpha level of 5% was chosen for statistical significance, with 95% CI presented. RESULTS: Significant between-group differences at post-intervention were observed for PF Z-score (β=0.24, [95%CI: 0.17;0.30] (ES:0.97), Grip-strength (β=1.8 [0.8;2.8] kg (ES:0.48), 30-sec-chair-stand (β=1.3 [0.7; 1.8] repetitions (ES: 0.63), Back scratch (β=2.1 [0.8;3.5] cm (ES:0.43), and Timed-up-and-go (β=−0.3 [−0.4;−0.2] seconds (ES:0.71). No significant between-group differences post-intervention were observed for Chair-sit-and-reach and One-leg standing tests. CONCLUSION: These findings indicate that healthy older adults can enhance their PF through a 6-month home-based HIIT intervention. However, no significant effects were observed in joint flexibility of the lower extremities or static balance ability. Nonetheless, these findings reinforce the potential of HIIT as a valuable component in public health strategies for promoting physical function in healthy older adults. REFERENCES: 1. Fragala et al., J Strength Cond Res, 2019 2. Schaun et al., Exp Gerontol, 2021 3. Herrod et al., GeroScience, 2021 4. Marriott et al., Sports Medicine Open, 2021 5. Gray et al., BJSM, 2016

• Albrecht, Mikael André; Segaert, Katrien; Fernandes, Eunice Gomes; Wetterlin, Allison Louise & Wheeldon, Linda Ruth (2025). Fluency and complexity in speech production: effects of healthy ageing. Fulltekst i vitenarkiv
• Fernandes, Eunice Gomes; Fosstveit, Sindre Herskedal; Feron, Jack; Rahman, Foyzul; Lucas, Samuel J.E. & Lohne-Seiler, Hilde [Vis alle 10 forfattere av denne artikkelen] (2024). Exercise training speeds language comprehension for monolingual but not bilingual older adults: evidence from a randomised controlled trial. Fulltekst i vitenarkiv
• Prystauka, Yanina; Tsvetanov, Kamen; Rahman, Foyzul; Feron, Jack; Fernandes, Eunice Gomes & Wetterlin, Allison Louise [Vis alle 9 forfattere av denne artikkelen] (2024). Does regular physical exercise mitigate age-related decline in word production? Fulltekst i vitenarkiv
• Fosstveit, Sindre Herskedal; Lohne-Seiler, Hilde; Feron, Jack; Joyce, Kelsey; Segaert, Katrien & Lucas, Samuel J.E. [Vis alle 7 forfattere av denne artikkelen] (2024). Enhancing cardiorespiratory fitness in older adults – HIIT at Home, a randomised controlled trial. Fulltekst i vitenarkiv

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