Utdanning:
Ph.D. i medisin (University of Oslo, 2014)
Praktisk pedagogisk utdanning (Universitetet i Oslo, 2006)
Cand. scient. molekylærbiologi (University of Bergen, 2004)
Arbeidserfaring:
2018- Postdoktor: ECOGENOME: A multispecies, multithrophic genomics apprach to costal ecosystem structure
2017- Forsker, ELIXIR, Universitetet i Oslo
2016-2018 Postdoktor. Havkyst Program. Naturlig seleksjon eller plastisitet som reaksjon på stor skala translokasjon og høsting over en klimatisk gradient i marine økosystem?
2014-2016 Lektor, Videregående opplæring, Vest-Agder fylkeskommune
2006-2009 Bioinfomratiker, Bioinformatic core facility, Oslo Universitetssykehus
2004-2006 Bioinfomratiker, Avdeling for medisinsk genetikk, Ullevål Universitetssykehus
Next-generation sequencing, genome assembly, population genetics and comparative genomics.
BIO113-1 - Evolutionary Biology
2018- A multispecies, multithrophic genomics apprach to costal ecosystem structure (ECOGENOME)
2014-2018 Postdoktor. Havkyst Program. Naturlig seleksjon eller plastisitet som reaksjon på stor skala translokasjon og høsting over en klimatisk gradient i marine økosystem?
Siste 5 år:
Mattingsdal M, Jentoft S, Torresen OK, Knutsen H, Hansen MM, Robalo JI, et al. A continuous genome assembly of the corkwing wrasse (Symphodus melops). Genomics. 2018.
Christoforou A, Dondrup M, Mattingsdal M, Mattheisen M, Giddaluru S, Nothen MM, et al. Linkage-disequilibrium-based binning affects the interpretation of GWASs. Am J Hum Genet. 2012;90(4):727-33.
Mattingsdal M, Brown AA, Djurovic S, Sonderby IE, Server A, Melle I, et al. Pathway analysis of genetic markers associated with a functional MRI faces paradigm implicates polymorphisms in calcium responsive pathways. Neuroimage. 2013;70:143-9.
Maier R, Moser G, Chen GB, Ripke S, Cross-Disorder Working Group of the Psychiatric Genomics C, Coryell W, et al. Joint analysis of psychiatric disorders increases accuracy of risk prediction for schizophrenia, bipolar disorder, and major depressive disorder. Am J Hum Genet. 2015;96(2):283-94.
Vilhjalmsson BJ, Yang J, Finucane HK, Gusev A, Lindstrom S, Ripke S, et al. Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores. Am J Hum Genet. 2015;97(4):576-92.
Bigdeli TB, Ripke S, Bacanu SA, Lee SH, Wray NR, Gejman PV, et al. Genome-wide association study reveals greater polygenic loading for schizophrenia in cases with a family history of illness. Am J Med Genet B Neuropsychiatr Genet. 2016;171B(2):276-89.
Duncan L, Yilmaz Z, Gaspar H, Walters R, Goldstein J, Anttila V, et al. Significant Locus and Metabolic Genetic Correlations Revealed in Genome-Wide Association Study of Anorexia Nervosa. Am J Psychiatry. 2017;174(9):850-8.
Srinivasan S, Bettella F, Mattingsdal M, Wang Y, Witoelar A, Schork AJ, et al. Genetic Markers of Human Evolution Are Enriched in Schizophrenia. Biol Psychiatry. 2016;80(4):284-92.
Goulart LF, Bettella F, Sonderby IE, Schork AJ, Thompson WK, Mattingsdal M, et al. MicroRNAs enrichment in GWAS of complex human phenotypes. Bmc Genomics. 2015;16:304.
Bipolar D, Schizophrenia Working Group of the Psychiatric Genomics Consortium. Electronic address drve, Bipolar D, Schizophrenia Working Group of the Psychiatric Genomics C. Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes. Cell. 2018;173(7):1705-15 e16.
de Jong S, Diniz MJA, Saloma A, Gadelha A, Santoro ML, Ota VK, et al. Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder. Commun Biol. 2018;1:163.
Lee SH, Byrne EM, Hultman CM, Kahler A, Vinkhuyzen AA, Ripke S, et al. New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis. Int J Epidemiol. 2015;44(5):1706-21.
Andreassen OA, Harbo HF, Wang Y, Thompson WK, Schork AJ, Mattingsdal M, et al. Genetic pleiotropy between multiple sclerosis and schizophrenia but not bipolar disorder: differential involvement of immune-related gene loci. Mol Psychiatry. 2015;20(2):207-14.
Hinney A, Kesselmeier M, Jall S, Volckmar AL, Focker M, Antel J, et al. Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index. Mol Psychiatry. 2017;22(2):192-201.
Huckins LM, Hatzikotoulas K, Southam L, Thornton LM, Steinberg J, Aguilera-McKay F, et al. Investigation of common, low-frequency and rare genome-wide variation in anorexia nervosa. Mol Psychiatry. 2018;23(5):1169-80.
McLaughlin RL, Schijven D, van Rheenen W, van Eijk KR, O'Brien M, Kahn RS, et al. Genetic correlation between amyotrophic lateral sclerosis and schizophrenia. Nat Commun. 2017;8:14774.
Bulik-Sullivan BK, Loh PR, Finucane HK, Ripke S, Yang J, Schizophrenia Working Group of the Psychiatric Genomics C, et al. LD Score regression distinguishes confounding from polygenicity in genome-wide association studies. Nat Genet. 2015;47(3):291-5.
Loh PR, Bhatia G, Gusev A, Finucane HK, Bulik-Sullivan BK, Pollack SJ, et al. Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance-components analysis. Nat Genet. 2015;47(12):1385-92.
Marshall CR, Howrigan DP, Merico D, Thiruvahindrapuram B, Wu W, Greer DS, et al. Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects. Nat Genet. 2017;49(1):27-35.
Franke B, Stein JL, Ripke S, Anttila V, Hibar DP, van Hulzen KJE, et al. Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept. Nat Neurosci. 2016;19(3):420-31.
Network, Pathway Analysis Subgroup of Psychiatric Genomics C. Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways. Nat Neurosci. 2015;18(2):199-209.
Sekar A, Bialas AR, de Rivera H, Davis A, Hammond TR, Kamitaki N, et al. Schizophrenia risk from complex variation of complement component 4. Nature. 2016;530(7589):177-83.
Andreassen OA, Thompson WK, Schork AJ, Ripke S, Mattingsdal M, Kelsoe JR, et al. Correction: Improved Detection of Common Variants Associated with Schizophrenia and Bipolar Disorder Using Pleiotropy-Informed Conditional False Discovery Rate. PLoS Genet. 2015;11(11):e1005544.
Andreassen OA, Desikan RS, Wang Y, Thompson WK, Schork AJ, Zuber V, et al. Correction: Abundant Genetic Overlap between Blood Lipids and Immune-Mediated Diseases Indicates Shared Molecular Genetic Mechanisms. PLoS One. 2015;10(5):e0128048.
Andreassen OA, Desikan RS, Wang Y, Thompson WK, Schork AJ, Zuber V, et al. Abundant genetic overlap between blood lipids and immune-mediated diseases indicates shared molecular genetic mechanisms. PLoS One. 2015;10(4):e0123057.
Tesli M, Kauppi K, Bettella F, Brandt CL, Kaufmann T, Espeseth T, et al. Altered Brain Activation during Emotional Face Processing in Relation to Both Diagnosis and Polygenic Risk of Bipolar Disorder. PLoS One. 2015;10(7):e0134202.
Kauppi K, Westlye LT, Tesli M, Bettella F, Brandt CL, Mattingsdal M, et al. Polygenic risk for schizophrenia associated with working memory-related prefrontal brain activation in patients with schizophrenia and healthy controls. Schizophr Bull. 2015;41(3):736-43.
Li D, Chang X, Connolly JJ, Tian L, Liu Y, Bhoj EJ, et al. Erratum: A genome-wide association study of anorexia nervosa suggests a risk locus implicated in dysregulated leptin signaling. Sci Rep. 2017;7(1):8379.
Li D, Chang X, Connolly JJ, Tian L, Liu Y, Bhoj EJ, et al. A genome-wide association study of anorexia nervosa suggests a risk locus implicated in dysregulated leptin signaling. Sci Rep. 2017;7(1):3847.
Ni G, Gratten J, Wray NR, Lee SH, Schizophrenia Working Group of the Psychiatric Genomics C. Age at first birth in women is genetically associated with increased risk of schizophrenia. Sci Rep. 2018;8(1):10168.
Brainstorm C, Anttila V, Bulik-Sullivan B, Finucane HK, Walters RK, Bras J, et al. Analysis of shared heritability in common disorders of the brain. Science. 2018;360(6395).
Sist endret: 15.11.2018 15:11